Department of Natural Products, National Institute of Pharmaceutical Education and Research (NIPER), Sector-67, S.A.S. Nagar, Punjab-160062, India.
Fitoterapia. 2011 Oct;82(7):1118-22. doi: 10.1016/j.fitote.2011.07.009. Epub 2011 Jul 23.
Two new naturally occurring formylated phloroglucinol compounds (FPCs), a dimer, loxophlebal B (10) and a cyclized FPC, loxophlebene (8) together with eight other formylated phloroglucinols (1-7 and 9) were isolated from the chloroform-methanol (8:2) extract of the leaves of Eucalyptus loxophleba ssp. lissophloia. The structures of new compounds were established by comprehensive spectral analysis and by comparison of their NMR data with those of related compounds in the literature. All the isolated compounds were evaluated for anti-leishmanial activity against promastigotes of Leishmania donovani.
从桉叶麻叶桉的叶的氯仿-甲醇（8:2）提取物中分离得到两种新的天然存在的甲酰基间苯三酚化合物（FPC），二聚体loxophlebal B（10）和环化的 FPCloxophlebene（8）以及另外八种甲酰基间苯三酚（1-7 和 9）。新化合物的结构通过综合光谱分析以及与文献中相关化合物的 NMR 数据比较来确定。所有分离得到的化合物都针对利什曼原虫的前鞭毛体进行了抗利什曼原虫活性评价。
