红树林植物（卤蕨）的抗菌活性。

Antimicrobial activity of mangrove plant (Lumnitzera littorea).

机构信息

Institute of Oceanography and Maritime Studies, Kulliyyah of Science, International Islamic University Malaysia, Jalan Sultan Ahmad Shah, Bandar Indera Mahkota, 25200 Kuantan, Pahang, Malaysia.

出版信息

Asian Pac J Trop Med. 2011 Jul;4(7):523-5. doi: 10.1016/S1995-7645(11)60138-7.

DOI:10.1016/S1995-7645(11)60138-7

PMID:21803301

Abstract

OBJECTIVE

To investigate the antimicrobial activities of n-hexane, ethyl acetate and methanol extracts of the leaves of Lumnitzera littorea (L. littorea) against six human pathogenic microbes.

METHODS

The antimicrobial activity was evaluated using disc diffusion and microdilution methods.

RESULTS

The antimicrobial activities of the crude extracts were increased with increasing the concentration. It is clear that n-hexane extract was the most effective extract. Additionally, Gram positive Bacillus cereus (B. cereus) appear to be the most sensitive strain while Pseudomonas aeruginosa (P. aeruginosa) and the yeast strains (Candida albicans (C. albicans) and Cryptococcus neoformans (C. neoformans)) appear to be resistance to the tested concentrations since no inhibition zone was observed. The inhibition of microbial growth at concentration as low as 0.04 mg/mL indicated the potent antimicrobial activity of L. littorea extracts.

CONCLUSIONS

The obtained results are considered sufficient for further study to isolate the compounds responsible for the activity and suggesting the possibility of finding potent antibacterial agents from L. littorea extracts.

摘要

目的

研究角果木（Lumnitzera littorea）叶的正己烷、乙酸乙酯和甲醇提取物对 6 种人体致病微生物的抗菌活性。

方法

采用圆盘扩散法和微量稀释法评价抗菌活性。

结果

随着浓度的增加，粗提取物的抗菌活性增强。正己烷提取物是最有效的提取物。此外，革兰氏阳性菌蜡样芽孢杆菌（Bacillus cereus）似乎是最敏感的菌株，而铜绿假单胞菌（Pseudomonas aeruginosa）和酵母菌株（白色念珠菌（Candida albicans）和新型隐球菌（Cryptococcus neoformans））似乎对测试浓度有耐药性，因为没有观察到抑菌圈。在低至 0.04mg/ml 的浓度下抑制微生物生长表明角果木提取物具有很强的抗菌活性。