Hôpital Cochin Assistance Publique des Hôpitaux de Paris (AP-HP), Paris V, France.
Leuk Res. 2011 Nov;35(11):1530-3. doi: 10.1016/j.leukres.2011.07.007. Epub 2011 Jul 30.
We evaluated the prognostic value of serum ferritin (SF) level at diagnosis in 318 newly diagnosed IPSS low and int 1 (lower) risk MDS patients included in the French MDS registry, who did not require RBC transfusions and had baseline SF level determination. Increased baseline SF level (>300 ng/ml) was correlated with male gender, more pronounced anaemia, and diagnosis of RARS but had no negative impact on progression to AML or survival.
我们评估了法国 MDS 登记处中 318 例新诊断的 IPSS 低危和中危 1 组（低危）MDS 患者的诊断时血清铁蛋白 (SF) 水平的预后价值，这些患者无需红细胞输注且基线 SF 水平可测定。基线 SF 水平升高（>300ng/ml）与男性、更明显的贫血和 RARS 诊断相关，但对进展为 AML 或生存无负面影响。
