Wolkowitz O M
Department of Psychiatry, University of California, San Francisco 94143.
Am J Ment Retard. 1990 Mar;94(5):509-14.
The correct methodology for performing the Dexamethasone Suppression Test (DST), which has been widely studied in psychiatry for its possible utility as a laboratory test of depression, was reviewed. Factors that may invalidate the test by producing false-positive or false-negative results and current recommendations regarding using the test were discussed. Studies of the use of the DST for patients with mental retardation as well as other patients displaying atypical symptoms of depression, such as children and demented elderly persons, were reviewed.
地塞米松抑制试验（DST）作为抑郁症的一项实验室检测可能具有的效用，已在精神病学领域得到广泛研究，本文对进行该试验的正确方法进行了综述。文中讨论了可能因产生假阳性或假阴性结果而使该试验无效的因素，以及目前关于使用该试验的建议。本文还综述了针对智力迟钝患者以及其他表现出非典型抑郁症状的患者（如儿童和老年痴呆症患者）使用DST的研究。
