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使用地塞米松抑制试验检测智力迟钝个体的抑郁症。

Use of the dexamethasone suppression test to detect depressive disorders of mentally retarded individuals.

作者信息

Pirodsky D M, Gibbs J W, Hesse R A, Hsieh M C, Krause R B, Rodriguez W H

出版信息

Am J Ment Defic. 1985 Nov;90(3):245-52.

PMID:4083305
Abstract

The applicability of the Dexamethasone Suppression Test (DST) with 39 mentally retarded individuals was examined. Subjects were assigned to one of three groups based upon the presence of zero, one, or two (or more) primary behaviors: unprovoked aggressive/assaultive behavior, self-injurious behavior, and severely withdrawn behavior. Chi-square analysis revealed that individuals exhibiting two or more of these types of behavior were more likely to obtain a positive DST result than were individuals exhibiting only one behavior. Results support the hypothesis that retarded persons can become depressed (as defined by the DST) and may express the depression through these behaviors. Furthermore, these results suggest that the current diagnostic criteria for depression in the retarded population need to be revised.

摘要

对39名智力迟钝者进行了地塞米松抑制试验(DST)的适用性研究。根据是否存在零种、一种或两种(或更多)主要行为将受试者分为三组:无端攻击/暴力行为、自我伤害行为和严重退缩行为。卡方分析显示,表现出两种或更多此类行为的个体比仅表现出一种行为的个体更有可能获得阳性DST结果。结果支持了这样的假设,即智力迟钝者可能会抑郁(根据DST定义),并可能通过这些行为表现出抑郁。此外,这些结果表明,目前针对智力迟钝人群的抑郁症诊断标准需要修订。

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1
Use of the dexamethasone suppression test to detect depressive disorders of mentally retarded individuals.使用地塞米松抑制试验检测智力迟钝个体的抑郁症。
Am J Ment Defic. 1985 Nov;90(3):245-52.
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The dexamethasone suppression test as an indication of depression in patients with mental retardation.
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Use of the dexamethasone suppression test with mentally retarded persons: review and recommendations.地塞米松抑制试验在智力迟钝者中的应用:综述与建议。
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Dexamethasone suppression test in primary depression: significance of family history and psychosis.原发性抑郁症的地塞米松抑制试验:家族史和精神病的意义
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引用本文的文献

1
Issues in the taxonomy of psychopathology in mental retardation.智力障碍中精神病理学分类的问题。
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