Sleep Medicine and Research Center, St. Luke’s Hospital, St. Louis, MO, USA.
Sleep. 2011 Aug 1;34(8):997-1011. doi: 10.5665/SLEEP.1150.
To explore the distribution of the 4 cardinal nighttime symptoms of insomnia-difficulty initiating sleep (DIS), difficulty maintaining sleep (DMS), early morning awakening (EMA), and nonrestorative sleep (NRS)-in a national sample of health plan members and the associations of these nighttime symptoms with sociodemographics, comorbidity, and perceived health.
DESIGN/SETTING/PARTICIPANTS: Cross-sectional telephone survey of 6,791 adult respondents.
None.
MEASUREMENTS/RESULTS: Current insomnia was assessed using the Brief Insomnia Questionnaire (BIQ)-a fully structured validated scale generating diagnoses of insomnia using DSM-IV-TR, ICD-10, and RDC/ICSD-2 inclusion criteria. DMS (61.0%) and EMA (52.2%) were more prevalent than DIS (37.7%) and NRS (25.2%) among respondents with insomnia. Sociodemographic correlates varied significantly across the 4 symptoms. All 4 nighttime symptoms were significantly related to a wide range of comorbid physical and mental conditions. All 4 also significantly predicted decrements in perceived health both in the total sample and among respondents with insomnia after adjusting for comorbid physical and mental conditions. Joint associations of the 4 symptoms predicting perceived health were additive and related to daytime distress/impairment. Individual-level associations were strongest for NRS. At the societal level, though, where both prevalence and strength of individual-level associations were taken into consideration, DMS had the strongest associations.
The extent to which nighttime insomnia symptoms are stable over time requires future long-term longitudinal study. Within the context of this limitation, the results suggest that core nighttime symptoms are associated with different patterns of risk and perceived health and that symptom-based subtyping might have value.
探索睡眠障碍的 4 个主要夜间症状(入睡困难、睡眠维持困难、早醒和睡眠质量差)在健康计划成员中的分布情况,并探讨这些夜间症状与社会人口统计学特征、合并症和感知健康的关系。
设计/环境/参与者:横断面电话调查了 6791 名成年受访者。
无。
测量/结果:使用简短失眠问卷(BIQ)评估当前失眠情况,BIQ 是一个完全结构化的经过验证的量表,根据 DSM-IV-TR、ICD-10 和 RDC/ICSD-2 纳入标准生成失眠诊断。在有失眠症状的受访者中,睡眠维持困难(61.0%)和早醒(52.2%)比入睡困难(37.7%)和睡眠质量差(25.2%)更为常见。社会人口统计学特征在 4 个症状中差异显著。所有 4 个夜间症状都与广泛的躯体和精神合并症显著相关。所有 4 个症状在调整躯体和精神合并症后,都显著预测了总样本和有失眠症状的受访者感知健康的下降。4 个症状联合预测感知健康具有累加性,与日间痛苦/障碍有关。在个体水平上,NRS 的相关性最强。然而,从社会层面考虑,即同时考虑了患病率和个体水平关联的强度,DMS 的关联最强。
夜间失眠症状在一段时间内的稳定程度需要未来进行长期纵向研究。在这一局限性的背景下,研究结果表明,核心夜间症状与不同的风险和感知健康模式相关,基于症状的亚分类可能具有价值。