Faritous Zahra S, Aghdaie Nahid, Yazdanian Forouzan, Azarfarin Rasoul, Dabbagh Ali
Department of Cardiac Anesthesiology, Shahid Rajaei Heart Center, Tehran, Iran.
Saudi J Anaesth. 2011 Apr;5(2):167-9. doi: 10.4103/1658-354X.82786.
Prolonged mechanical ventilation is an important recognized complication occurring during cardiovascular surgery procedures. This study was done to assess the perioperative risk factors related to postoperative pulmonary complications and tracheostomy in women undergoing coronary artery bypass graft with cardiopulmonary bypass.
It was a retrospective study on 5,497 patients, including 31 patients with prolonged ventilatory support and 5,466 patients without it; from the latter group, 350 patients with normal condition (extubated in 6-8 hours without any complication) were selected randomly. Possible perioperative risk factors were compared between the two groups using a binary logistic regression model.
Among the 5,497 women undergoing coronary artery bypass graft (CABG), 31 women needed prolonged mechanical ventilation (PMV), and 15 underwent tracheostomy. After logistic regression, 7 factors were determined as being independent perioperative risk factors for PMV.
Age ≥70 years old, left ventricular ejection fraction (LVEF) ≤30%, preexisting respiratory or renal disease, emergency or re-do operation and use of preoperative inotropic agents are the main risk factors determined in this study on women undergoing CABG.
长时间机械通气是心血管手术过程中一种公认的重要并发症。本研究旨在评估接受体外循环冠状动脉搭桥术的女性患者围手术期与术后肺部并发症及气管切开相关的危险因素。
这是一项对5497例患者的回顾性研究，其中包括31例需要长时间通气支持的患者和5466例不需要的患者；从后一组中随机选择350例情况正常（6 - 8小时内拔管且无任何并发症）的患者。使用二元逻辑回归模型比较两组可能的围手术期危险因素。
在5497例接受冠状动脉搭桥术（CABG）的女性患者中，31例女性需要长时间机械通气（PMV），15例行气管切开术。经过逻辑回归分析，确定7个因素为PMV的独立围手术期危险因素。
年龄≥70岁、左心室射血分数（LVEF）≤30%、既往有呼吸或肾脏疾病、急诊或再次手术以及术前使用正性肌力药物是本研究中接受CABG的女性患者的主要危险因素。
