非人灵长类动物的辅助生殖技术。
Assisted reproductive technology in nonhuman primates.
作者信息
Arthur Chang Tien-Cheng, Chan Anthony W S
机构信息
Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, School of Medicine, University of Texas Health Science Center, San Antonio, TX, USA.
出版信息
Methods Mol Biol. 2011;770:337-63. doi: 10.1007/978-1-61779-210-6_13.
Nonhuman primates (NHP) are the closest animal species to humans and have been widely used for studying human reproductive physiology. Assisted reproductive technology (ART) in Old World NHPs provides great opportunity for studying fertilization, embryo development, embryonic stem cell (ESC) derivation for regenerative medicine, somatic cell nuclear transfer (cloning), and transgenic NHP models of inherited genetic disorders. Here we present two ART protocols developed for rhesus monkey (Macaca mulatta) and baboon (Papio cynocephalus).
非人灵长类动物（NHP）是与人类亲缘关系最近的动物物种，已被广泛用于研究人类生殖生理学。旧世界非人灵长类动物的辅助生殖技术（ART）为研究受精、胚胎发育、用于再生医学的胚胎干细胞（ESC）衍生、体细胞核移植（克隆）以及遗传性遗传疾病的转基因非人灵长类动物模型提供了绝佳机会。在此，我们展示了为恒河猴（猕猴）和狒狒（黄狒）开发的两种辅助生殖技术方案。
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