Mäkelä Mika, Kulmala Petri, Pelkonen Anna, Remes Sami, Kuitunen Mikael
HYKS:n Iho-ja Allergiasairaala, HUS.
Duodecim. 2011;127(12):1263-71.
Although most infants will recover from food allergy within the early years of life, at least one fifth will carry on with the disease until school age. Recent studies have managed to develop increased tolerance in children with food allergy by food hyposensitization with slowly increasing orally administered doses. In these studies either complete or partial increase of food tolerance for 80% of subjects has been achieved. The clinical results seem promising, and immunologic changes upon food hyposensitization look similar to those observed with other hyposensitization therapies.
尽管大多数婴儿会在生命的早期从食物过敏中康复，但至少五分之一的婴儿会持续患有这种疾病直到学龄期。最近的研究通过缓慢增加口服剂量的食物减敏疗法，成功提高了食物过敏儿童的耐受性。在这些研究中，80%的受试者实现了食物耐受性的完全或部分提高。临床结果似乎很有前景，食物减敏疗法后的免疫变化与其他减敏疗法所观察到的相似。
