Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, CA, USA.
Expert Rev Anticancer Ther. 2011 Jul;11(7):1077-89. doi: 10.1586/era.11.83.
Patients with gynecologic cancer experience significant symptom burden throughout their disease course and treatment, which negatively impacts their quality of life. The most common symptoms in gynecologic cancer include pain, fatigue, depression and anxiety. Palliative care, including symptom management, focuses on the prevention and relief of suffering and improvement in quality of life, irrespective of prognosis. In a comprehensive cancer care model, palliative care, including symptom management, is offered concurrently with anticancer therapies throughout the disease course, not just at the end of life and not only once curative attempts have been abandoned. Good symptom management begins with routine symptom assessment and use of a standardized screening tool can help identify patients with high symptom burden. Literature regarding epidemiology, assessment and management of pain, fatigue, nausea/vomiting, lymphedema, ascites, depression, anxiety and sexual dysfunction in gynecologic oncology patients will be reviewed in this article.
妇科癌症患者在疾病过程和治疗中会经历显著的症状负担，这会对他们的生活质量产生负面影响。妇科癌症中最常见的症状包括疼痛、疲劳、抑郁和焦虑。姑息治疗，包括症状管理，侧重于预防和缓解痛苦以及改善生活质量，而不考虑预后。在综合癌症治疗模式中，姑息治疗，包括症状管理，与抗癌治疗同时提供，贯穿疾病过程，而不仅仅是在生命末期，也不仅仅是在放弃治愈尝试之后。良好的症状管理始于常规症状评估，使用标准化筛查工具可以帮助识别出具有高症状负担的患者。本文将回顾妇科肿瘤患者疼痛、疲劳、恶心/呕吐、淋巴水肿、腹水、抑郁、焦虑和性功能障碍的流行病学、评估和管理方面的文献。
