• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

拳师犬非综合征性唇腭裂：单基因常染色体隐性遗传的证据

Nonsyndromic cleft lip and palate in boxer dogs: evidence of monogenic autosomal recessive inheritance.

作者信息

Moura Enio, Cirio Silvana M, Pimpão Cláudia T

机构信息

Service of Medical Genetics, Faculty of Veterinary Medicine, Campus Sao Jose, Pontifıcia Universidade Catolica do Parana , Rua Imaculada Conceicao, 1155, 80215-901 Curitiba, PR, Brazil.

出版信息

Cleft Palate Craniofac J. 2012 Nov;49(6):759-60. doi: 10.1597/11-110. Epub 2011 Aug 1.

DOI:10.1597/11-110
PMID:21806339
Abstract

Four newborn boxer dogs with bilateral cleft lip and palate were examined in search of further abnormalities, but no other type of congenital defect was found. These data, along with the pedigree inspection regarding the clinical phenotype, led to the conclusion that the affected dogs had a nonsyndromic monogenic autosomal recessive cleft lip and palate.

摘要

对4只患有双侧唇腭裂的新生拳师犬进行了检查，以寻找其他异常情况，但未发现其他类型的先天性缺陷。这些数据，连同对临床表型的系谱检查，得出结论：受影响的犬患有非综合征性单基因常染色体隐性唇腭裂。

相似文献

1
Nonsyndromic cleft lip and palate in boxer dogs: evidence of monogenic autosomal recessive inheritance.拳师犬非综合征性唇腭裂：单基因常染色体隐性遗传的证据
Cleft Palate Craniofac J. 2012 Nov;49(6):759-60. doi: 10.1597/11-110. Epub 2011 Aug 1.
2
Cleft lip and/or palate with monogenic autosomal recessive transmission in Pyrenees shepherd dogs.比利牛斯牧羊犬中具有单基因常染色体隐性遗传的唇腭裂。
Cleft Palate Craniofac J. 2009 Jan;46(1):81-8. doi: 10.1597/06-229.1. Epub 2008 Mar 5.
3
Genetic studies of cleft lip and palate in dogs.犬唇腭裂的遗传学研究。
Birth Defects Orig Artic Ser. 1971 Jun;7(7):98-100.
4
Observations about the normal and abnormal embryogenesis of the canine lip and palate.关于犬唇部和腭部正常及异常胚胎发生的观察。
J Craniofac Genet Dev Biol Suppl. 1986;2:241-8.
5
Tibial hemimelia-cleft lip/palate in a Brazilian child born to consanguineous parents.一名父母近亲结婚的巴西儿童患胫骨半肢畸形-唇腭裂。
Am J Med Genet. 1987 Oct;28(2):325-9. doi: 10.1002/ajmg.1320280209.
6
Dermatoglyphics and Cheiloscopy as Key Tools in Resolving the Genetic Correlation of Inheritance Patterns in Cleft Lip and Palate Patients: An Assessment of 160 Patients.皮纹学和唇纹学作为解决唇腭裂患者遗传模式遗传相关性的关键工具：对160例患者的评估
Cleft Palate Craniofac J. 2017 Sep;54(5):588-594. doi: 10.1597/15-168. Epub 2016 May 25.
7
Genetic studies of a cleft palate clinic population.腭裂门诊患者群体的遗传学研究。
Birth Defects Orig Artic Ser. 1971 Jun;7(7):54-7.
8
17p13.3 microduplication, a potential novel genetic locus for nonsyndromic bilateral cleft lip and palate.17p13.3微重复，一种非综合征性双侧唇腭裂潜在的新基因位点。
Cleft Palate Craniofac J. 2015 May;52(3):359-62. doi: 10.1597/13-113. Epub 2014 Mar 13.
9
Investigation of dominant and recessive inheritance models in genome-wide association studies data of nonsyndromic cleft lip with or without cleft palate.非综合征型唇裂伴或不伴腭裂全基因组关联研究数据中显性和隐性遗传模型的研究。
Birth Defects Res. 2018 Mar 1;110(4):336-341. doi: 10.1002/bdr2.1144. Epub 2017 Nov 14.
10
A lethal, unclassifiable form of micromelic dwarfism with posterior cleft palate, multiple cervicothoracal vertebral anomalies and iliac hypoplasia: evidence for autosomal recessive inheritance.一种伴有后腭裂、多发颈胸椎椎体异常和髂骨发育不全的致死性、无法分类的短肢侏儒症：常染色体隐性遗传的证据
Genet Couns. 1998;9(1):61-2.

引用本文的文献

1
Craniofacial malformations in a stillborn mixed-breed dog as a cause for dystocia.一例难产致死胎杂种犬颅面部畸形病例报告
Vet Med Sci. 2024 Sep;10(5):e70010. doi: 10.1002/vms3.70010.
2
Exceptional Changes in Skeletal Anatomy under Domestication: The Case of Brachycephaly.驯化过程中骨骼解剖结构的异常变化：短头畸形的案例
Integr Org Biol. 2021 Aug 16;3(1):obab023. doi: 10.1093/iob/obab023. eCollection 2021.
3
Prenatal diagnosis of foetal hydrocephalus and suspected X-linked recessive inheritance of cleft lip in a Chihuahua.
一只吉娃娃犬胎儿脑积水的产前诊断及唇裂疑似X连锁隐性遗传
J Vet Med Sci. 2020 Feb 18;82(2):212-216. doi: 10.1292/jvms.18-0516. Epub 2019 Dec 27.
4
Incidence patterns of orofacial clefts in purebred dogs.纯种犬发生口面裂的模式。
PLoS One. 2019 Nov 4;14(11):e0224574. doi: 10.1371/journal.pone.0224574. eCollection 2019.
5
Computed tomographic evaluation of cleft palate in one-day-old puppies.一日龄幼犬腭裂的计算机断层扫描评估
BMC Vet Res. 2018 Oct 20;14(1):316. doi: 10.1186/s12917-018-1642-6.
6
Management of Cleft Palate in Puppies Using A Temporary Prosthesis: A Report of Three Cases.使用临时假体治疗幼犬腭裂：三例报告
Vet Sci. 2018 Jun 24;5(3):61. doi: 10.3390/vetsci5030061.
7
Exploring the Underlying Genetics of Craniofacial Morphology through Various Sources of Knowledge.通过多种知识来源探索颅面形态学的潜在遗传学。
Biomed Res Int. 2016;2016:3054578. doi: 10.1155/2016/3054578. Epub 2016 Dec 8.
8
Genome-wide association studies in dogs and humans identify ADAMTS20 as a risk variant for cleft lip and palate.在狗和人类中进行的全基因组关联研究将ADAMTS20鉴定为唇腭裂的一个风险变异体。
PLoS Genet. 2015 Mar 23;11(3):e1005059. doi: 10.1371/journal.pgen.1005059. eCollection 2015 Mar.
9
A LINE-1 insertion in DLX6 is responsible for cleft palate and mandibular abnormalities in a canine model of Pierre Robin sequence.DLX6基因中的LINE-1插入导致了皮埃尔·罗宾序列犬模型中的腭裂和下颌骨异常。
PLoS Genet. 2014 Apr 3;10(4):e1004257. doi: 10.1371/journal.pgen.1004257. eCollection 2014 Apr.