[原发性骨髓增生异常综合征中的染色体变化]
[Chromosomal changes in primary myelodysplasias].
作者信息
Iavorkovskiĭ L I, Riauzova L Iu, Soloveĭ E Ia, Iavorkovskiĭ L L
出版信息
Eksp Onkol. 1990;12(2):10-6.
PMID:2180674
Abstract
The data from literature on chromosome abnormalities in various subgroups of the myelodysplastic syndrome (according to FAB-classification) are presented. Special attention is paid to information about changes in the number and structure of chromosomes during the disease and their prognostic significance. The relation of definite chromosome aberrations to the clinical course and prognosis of the disease, in particular to its transformation into acute leukosis is under discussion.
摘要
本文展示了有关骨髓增生异常综合征各亚组（根据FAB分类）染色体异常的文献数据。特别关注了疾病过程中染色体数量和结构变化的信息及其预后意义。正在讨论特定染色体畸变与疾病临床进程和预后的关系，尤其是与疾病转化为急性白血病的关系。
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