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前额叶经颅磁刺激对自发说实话的影响。

Effect of prefrontal transcranial magnetic stimulation on spontaneous truth-telling.

机构信息

Institute of Psychology, University of Tartu, 78 Tiigi Street, 50410 Tartu, Estonia.

出版信息

Behav Brain Res. 2011 Nov 20;225(1):209-14. doi: 10.1016/j.bbr.2011.07.028. Epub 2011 Jul 22.

Abstract

Brain-process foundations of deceptive behaviour have become a subject of intensive study both in fundamental and applied neuroscience. Recently, utilization of transcranial magnetic stimulation has enhanced methodological rigour in this research because in addition to correlational studies causal effects of the distinct cortical systems involved can be studied. In these studies, dorsolateral prefrontal cortex has been implied as the brain area involved in deceptive behaviour. However, combined brain imaging and stimulation research has been concerned mostly with deceptive behaviour in the contexts of mock thefts and/or denial of recognition of critical objects. Spontaneous, "criminally decontextuated" propensity to lying and its dependence on the activity of selected brain structures has remained unexplored. The purpose of this work is to test whether spontaneous propensity to lying can be changed by brain stimulation. Here, we show that when subjects can name the colour of presented objects correctly or incorrectly at their free will, the tendency to stick to truthful answers can be manipulated by stimulation targeted at dorsolateral prefrontal cortex. Right hemisphere stimulation decreases lying, left hemisphere stimulation increases lying. Spontaneous choice to lie more or less can be influenced by brain stimulation.

摘要

欺骗行为的大脑处理基础已成为基础和应用神经科学领域的研究热点。最近,经颅磁刺激的应用提高了该研究的方法严谨性,因为除了相关研究外,还可以研究涉及的不同皮质系统的因果效应。在这些研究中,背外侧前额叶皮层被认为是与欺骗行为相关的脑区。然而,联合脑成像和刺激研究主要集中在模拟盗窃和/或否认关键物体识别背景下的欺骗行为。自发性、“犯罪去情境化”的说谎倾向及其对选定脑结构活动的依赖性仍未得到探索。本工作的目的是检验大脑刺激是否可以改变自发性的说谎倾向。在这里,我们表明,当受试者可以自由选择正确或错误地命名呈现的物体的颜色时,刺激背外侧前额叶皮层可以操纵坚持真实答案的倾向。右半球刺激减少说谎,左半球刺激增加说谎。通过大脑刺激可以影响自发性的说谎程度。

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