Kaste Sue C
Department of Radiological Sciences, St. Jude Children's Research Hospital, MSN #220, 262 Danny Thomas Place, Memphis, TN 38105, USA.
Radiol Clin North Am. 2011 Jul;49(4):749-65, vi-vii. doi: 10.1016/j.rcl.2011.05.006. Epub 2011 Jun 16.
Primary malignant bone tumors are rare and account for about 6% of all new pediatric cancer cases per year in the United States. Identification of the lesion not uncommonly occurs as a result of imaging performed for trauma. Clinical and standard imaging characteristics of the various tumor types are evolving in concert with treatment advancements and clinical trial regimens. This article reviews the 3 most common pediatric bone sarcomas-osteosarcoma, Ewing sarcoma, and chondrosarcoma-and their imaging as applicable to contemporary disease staging and monitoring, and explores the roles of evolving imaging techniques.
原发性恶性骨肿瘤较为罕见,在美国每年约占所有儿童新发癌症病例的6%。因外伤进行影像学检查时,病变的识别并不少见。随着治疗进展和临床试验方案的推进,各种肿瘤类型的临床和标准影像学特征也在不断演变。本文回顾了3种最常见的儿童骨肉瘤——骨肉瘤、尤因肉瘤和软骨肉瘤——及其在当代疾病分期和监测中的影像学表现,并探讨了不断发展的影像学技术的作用。