Snyder Institute for Infection, Inflammation and Immunity, University of Calgary, Alberta, Canada.
Ther Adv Respir Dis. 2011 Oct;5(5):305-24. doi: 10.1177/1753465811398720. Epub 2011 Aug 1.
Pulmonary mycoses are among the most feared infections encountered in immunocompromised patients. The problem is amplified by the increasing numbers of chronically immunocompromised patients that have substantially increased both the prevalence and clinical severity of infections caused by fungi. Moreover, fungal infections in this patient population pose challenges in diagnosis and management. Fortunately, recent advances in diagnostics and antifungal therapy, and their direct application to specific diseases, provide important new approaches to this complex and often seriously ill patient population. In this article we review the commonly occurring pulmonary fungal infections in the immunocompromised population with a particular focus on their management.
肺部真菌感染是免疫功能低下患者最担心的感染之一。由于慢性免疫功能低下患者的数量不断增加，真菌感染的患病率和临床严重程度都大大增加，这一问题进一步加剧。此外，此类患者人群中的真菌感染在诊断和治疗方面也存在挑战。幸运的是，最近在诊断和抗真菌治疗方面的进展，以及它们在特定疾病中的直接应用，为这一复杂且通常病情严重的患者群体提供了重要的新方法。本文重点介绍了免疫功能低下人群中常见的肺部真菌感染，并对其治疗进行了综述。
