ENT Clinic, Department of Surgical, Experimental and Clinical Sciences, "G. D'Annunzio" University of Chieti- Pescara, Italy.
Acta Otorhinolaryngol Ital. 2011 Feb;31(1):5-10.
Lip cancer is the most frequent malignant neoplasm of the oral cavity. The study reported herewith refers to the clinico-pathological features and surgical treatment of lip cancer. The most frequent tumour related to the lips is squamous cell carcinoma, with the lower lip more commonly involved than the upper lip. Typically, squamous cell carcinoma originates in the red lip, whereas basal cell carcinoma involves the white lip. The management of lip cancer involves the control not only of the primary tumours with oncologically appropriate margins and subsequent reconstruction to allow oral competence during the oral phase of swallowing, but also the possible metastatic spread to the neck. Reconstruction is a surgical challenge especially for advanced and extended lesions. A successful reconstruction depends on careful pre-operative planning, knowledge of the anatomy and use of the various surgical techniques. Lymph node neck metastases significantly reduce long-term survival. Although the management of the neck is controversial in lip cancer, particularly with respect to the neck, elective or curative supra-omohyoid neck dissection is the best choice for occult or evident loco-regional metastases. Early stage tumours have good prognostic, aesthetic and functional results after surgery compared to the treatment of advanced lesions, which alter the appearance and functionality of the lip. The Authors report their experience in the treatment of lip tumours at the primary site, considering reconstructive problems, together with management of neck metastases.
唇癌是口腔最常见的恶性肿瘤。本研究报告了唇癌的临床病理特征和外科治疗。与唇部最相关的肿瘤通常是鳞状细胞癌,而下唇比上唇更常见受累。典型的鳞状细胞癌起源于红唇,而基底细胞癌则累及白唇。唇癌的治疗不仅包括通过适当的肿瘤学边缘控制原发性肿瘤,并随后进行重建以在吞咽的口腔阶段保持口腔功能,还包括可能发生的颈部转移。重建是一个手术挑战,特别是对于晚期和广泛病变。成功的重建取决于术前的精心规划、对解剖结构的了解和各种手术技术的运用。淋巴结颈部转移显著降低了长期生存率。尽管在唇癌的颈部管理方面存在争议,特别是在颈部方面,对于隐匿性或明显的局部区域转移,选择性或根治性颈清扫术是最佳选择。与治疗晚期病变相比,早期肿瘤在手术后具有良好的预后、美学和功能结果,晚期病变会改变唇的外观和功能。作者报告了他们在原发性唇肿瘤治疗方面的经验,考虑到了重建问题以及颈部转移的处理。