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患者人口统计学特征和肿瘤特性对唇癌重建技术的影响。

Influence of the patient's demographic profile and tumor characteristics on reconstructive techniques in lip cancers.

作者信息

Ţânţu Ana Cătălina, Ciurea Marius Eugen, Dumitrache Vasilica Mihaela, Păunescu Alina, Ţânţu Marilena Monica, Ciucurel Constantin, Iconaru Elena Ioana, Diaconescu Daniel Corneliu, Ionescu Georgeta, Man George Mihail, Honţaru Sorina Octavia, Dicu Consuela, Popescu George

机构信息

Department of Medical Assistance and Kinetotherapy, Faculty of Sciences, Physical Education and Informatics, University Center Piteşti, National University of Science and Technology Politehnica Bucharest, Piteşti, Romania;

出版信息

Rom J Morphol Embryol. 2025 Jan-Mar;66(1):229-238. doi: 10.47162/RJME.66.1.21.

DOI:10.47162/RJME.66.1.21
PMID:40384208
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12236273/
Abstract

With an incidence of approximately 30% of all oral cavity neoplasms, lip cancer significantly impacts the patient quality of life (QoL). The frequent localization is in the lower lip, predominantly affecting men aged between 60-70 years old. The surgical treatment aims at aesthetic and functional reconstruction of the lip. The present study aims at defining a demographic profile of patients with lip cancer and at establishing correlations between tumor characteristics and reconstruction methods. The analysis of the group of 26 patients showed that the lip cancer patient was predominantly female, urban, with a mean age of 73.27±11.17 years old, with squamous cell carcinoma of the lower lip, mean diameter of 1.52 cm and mean depth of 0.72 cm. The tumor characteristics revealed a guide of the decision on the method of lip reconstruction, considering the correlations between a variety of factors, including the size of the affected area, etiology and location of the formation, integration of the flap into the relaxed skin tension lines, the patient general condition, and the degree of cooperation. Regardless of the reconstructive method chosen, the aim is to preserve the functions of the lip in mastication, speech and definition of facial expression. Complex cases require extensive reconstructive interventions involving combinations of various types of flaps. Multidisciplinary management of these patients leads to improved QoL and prevention of recurrences.

摘要

唇癌占所有口腔肿瘤的发病率约为30%,严重影响患者的生活质量(QoL)。其常见部位在下唇,主要影响60至70岁的男性。手术治疗旨在实现唇部的美学和功能重建。本研究旨在确定唇癌患者的人口统计学特征,并建立肿瘤特征与重建方法之间的相关性。对26例患者的分析表明,唇癌患者以女性为主,居住在城市,平均年龄为73.27±11.17岁,患有下唇鳞状细胞癌,平均直径为1.52 cm,平均深度为0.72 cm。肿瘤特征揭示了唇重建方法决策的指南,考虑了多种因素之间的相关性,包括受影响区域的大小、病变的病因和位置、皮瓣与松弛皮肤张力线的整合、患者的一般状况以及合作程度。无论选择何种重建方法,目的都是保留唇部在咀嚼、言语和面部表情界定方面的功能。复杂病例需要涉及各种类型皮瓣组合的广泛重建干预。对这些患者的多学科管理可改善生活质量并预防复发。

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本文引用的文献

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Original Personalized Reconstruction Method for Certain Large Tumors of the Lower Lip (Not Including Oral Commissures).下唇特定大型肿瘤(不包括口角)的原始个性化重建方法。
Medicina (Kaunas). 2024 Dec 24;61(1):4. doi: 10.3390/medicina61010004.
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Squamous cell carcinoma and basal cell carcinoma of the lips: 25 years of experience in a northeast Brazilian population.唇部鳞状细胞癌和基底细胞癌:巴西东北部人群 25 年的经验。
Med Oral Patol Oral Cir Bucal. 2024 Jul 1;29(4):e476-e482. doi: 10.4317/medoral.26454.
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Lower Lip Reconstruction after Skin Cancer Excision: A Tailored Algorithm for Elderly Patients.
皮肤癌切除术后下唇重建:针对老年患者的定制算法
J Clin Med. 2024 Jan 18;13(2):554. doi: 10.3390/jcm13020554.
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Primary repair with no flaps for lower lip defects (30-80 %) after cancer excision.对于癌症切除术后下唇缺损(30%-80%),采用无皮瓣的一期修复。
Asian J Surg. 2024 Feb;47(2):995-998. doi: 10.1016/j.asjsur.2023.12.124. Epub 2023 Dec 29.
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Tumor angiogenesis in gastric cancer.胃癌中的肿瘤血管生成。
Rom J Morphol Embryol. 2023 Jul-Sep;64(3):311-318. doi: 10.47162/RJME.64.3.03.
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Assessment of tumor microenvironment in gastric adenocarcinoma.胃腺癌肿瘤微环境评估。
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Simple lip reconstruction technique for middle-sized defects in lower lip cancer - Bilateral oblique mucosal V-Y advancement flap.下唇癌中等大小缺损的简单唇重建技术——双侧斜形黏膜 V-Y 推进瓣。
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