Zentrum für Endokrinologie, Kinderwunsch und Pränatale Medizin, amedes Hamburg, Germany.
Ultraschall Med. 2011 Aug;32(4):362-6. doi: 10.1055/s-0031-1273465. Epub 2011 Aug 1.
The objective of this study was to evaluate which cardiac planes and malformations can be visualized by first trimester fetal echocardiography during the daily routine in a prenatal medicine unit.
From October 2007 to June 2009, all fetuses with a crown rump length between 45 and 84 mm were included in the study. The fetal echocardiographies were carried out by one examiner. The entire examination including fetal echocardiography was completed within a time interval of 30 minutes. When possible, the abdominal plane, 4-chamber view (CV), pulmonary veins, left ventricular outflow tract, 3-vessel view (3-VV) and the aortic arch were visualized by color Doppler and/or power Doppler sonography.
690 fetuses were enrolled in the retrospective study. The abdominal plane, 4-CV, pulmonary veins, left ventricular outflow tract, 3-VV and the aortic arch were visualized in 99 %, 96 %, 23 %, 97 %, 98 % and 72 % of cases, respectively. During the study interval, 17 cardiac malformations were diagnosed. Outcome data were obtained in 92 % of the normal fetuses. 5 cardiac anomalies were diagnosed beyond the first trimester.
The standard planes of fetal echocardiography can be displayed in the first trimester in the clinical routine. Pulmonary veins can be visualized in almost a quarter of the cases. First trimester congenital heart diseases are strongly associated with chromosomal abnormalities during the first trimester.
本研究旨在评估在产前医学单位的日常工作中，通过胎儿早期心脏超声检查可以显示哪些心脏平面和畸形。
从 2007 年 10 月至 2009 年 6 月，所有头臀长在 45 至 84 毫米之间的胎儿均被纳入本研究。胎儿心脏超声检查由一名检查者进行。整个检查包括胎儿心脏超声检查，在 30 分钟的时间间隔内完成。当可能时，通过彩色多普勒和/或能量多普勒超声显示腹部平面、四腔心切面（CV）、肺静脉、左心室流出道、三血管切面（3-VV）和主动脉弓。
690 例胎儿被纳入回顾性研究。腹部平面、四腔心切面、肺静脉、左心室流出道、三血管切面和主动脉弓的显示率分别为 99%、96%、23%、97%、98%和 72%。在研究期间，诊断出 17 例心脏畸形。92%的正常胎儿获得了结局数据。5 例心脏异常在孕早期后被诊断出来。
在临床常规中，可以在孕早期显示胎儿心脏超声的标准平面。近四分之一的病例可以显示肺静脉。孕早期先天性心脏病与孕早期的染色体异常密切相关。
