School of Chemistry and Chemical Engineering, Huaiyin Normal University, Jiangsu Key Laboratory for Chemistry of Low-Dimensional Materials, Huaian 223300, PR China.
Nat Prod Res. 2012;26(14):1363-7. doi: 10.1080/14786419.2011.602828. Epub 2011 Aug 2.
This study investigated the antimicrobial and antioxidant activity of the extracts of the flowers, essential oil (EO) and semi-volatile fractions (SVF) of Chimonanthus praecox. The chemical composition of the EO was analysed by gas chromatography-mass spectroscopy (GC-MS) which revealed that the EO contained elemene, muurolene, caryophyllene, cadinol and spathulenol. The effective antibacterial activity of the EO suggested that its different responses on the microorganisms studied depended on the synergistic effects of the compounds contained in the EO. The effective antioxidant activity of the EO showed that the EO had a more marked antioxidant effect on scavenging O2(-)· and OH· than DPPH·, and SVF had a higher potential for scavenging DPPH· than the EO. Our data suggested that the flowers of Chimonanthus praecox had pharmaceutical benefits, and are also a potential source of natural antioxidants and biocides.
本研究调查了蜡梅鲜花、精油（EO）和半挥发性馏分（SVF）的提取物的抗菌和抗氧化活性。通过气相色谱-质谱联用（GC-MS）分析了 EO 的化学成分，结果表明 EO 含有榄香醇、愈创木烯、石竹烯、卡地醇和斯巴醇。EO 的有效抗菌活性表明，其对所研究微生物的不同反应取决于 EO 中所含化合物的协同作用。EO 的有效抗氧化活性表明，EO 对清除 O2(-)·和 OH·的抗氧化作用比 DPPH·更明显，而 SVF 对 DPPH·的清除能力比 EO 更高。我们的数据表明，蜡梅花具有药用价值，也是天然抗氧化剂和生物杀灭剂的潜在来源。
