诱导剂和抑制剂联合检测法在检测产 AmpC 酶铜绿假单胞菌中的诊断价值。
Diagnostic utility of combination of inducer and inhibitor based assay in detection of Pseudomonas aeruginosa producing AmpC β-lactamase.
机构信息
Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, India.
出版信息
J Microbiol Methods. 2011 Oct;87(1):116-8. doi: 10.1016/j.mimet.2011.07.012. Epub 2011 Jul 23.
PMID:21810447
Abstract
The diagnostic utility of inducer and inhibitor based assays among 214 AmpC positive isolates of Pseudomonas aeruginosa were evaluated. Of different methods, combination of ceftazidime-imipenem antagonism and boronic acid inhibition tests came up with maximum sensitivity (76%) and specificity (100%). This combination showed reliability for both inducible and non-inducible AmpC producers.
摘要
我们评估了在 214 株铜绿假单胞菌 AmpC 阳性分离株中基于诱导剂和抑制剂的检测方法的诊断效用。在不同的方法中，头孢他啶-亚胺培南拮抗与硼酸抑制试验的联合应用具有最高的敏感性（76%）和特异性（100%）。这种联合应用对于诱导型和非诱导型 AmpC 产生菌均具有可靠性。
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