产碳青霉烯酶肺炎克雷伯菌（KPC）耐药、多黏菌素耐药的肺炎克雷伯菌，属于国际流行克隆株 ST258。
Colistin-resistant, Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae belonging to the international epidemic clone ST258.
机构信息
Division of Infectious Diseases, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
出版信息
Clin Infect Dis. 2011 Aug;53(4):373-6. doi: 10.1093/cid/cir401.
Abstract
Five cases of infection due to colistin-resistant, Klebsiella pneumoniae carbapenemase-producing K. pneumoniae belonging to the international epidemic clone ST258 occurred over a 4-month period. These cases likely represented both emergence of resistance and transmission of resistant organism. The colistin-resistant isolates were able to persist in the absence of selective pressure in vitro.
摘要
在 4 个月的时间内，发生了 5 例由产碳青霉烯酶的耐粘菌素肺炎克雷伯菌（国际流行克隆株 ST258）引起的感染病例。这些病例可能既代表了耐药性的出现，也代表了耐药菌的传播。在没有体外选择压力的情况下，耐粘菌素的分离株能够持续存在。
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