aeruginazole A 的全合成。
Total synthesis of aeruginazole A.
机构信息
Institute for Research in Biomedicine, Barcelona Science Park, Carrer Baldiri Reixac 10, 08028 Barcelona, Spain.
出版信息
Org Lett. 2011 Sep 2;13(17):4648-51. doi: 10.1021/ol2018592. Epub 2011 Aug 3.
PMID:21812399
Abstract
The first total synthesis of Aeruginazole A, prepared via a convergent strategy that involved both solid-phase peptide synthesis and solution phase chemistry and that enabled conservation of the stereochemistry of the intermediates, is reported.
摘要
报道了 Aeruginazole A 的首次全合成，该合成采用了一种收敛策略，既涉及固相肽合成又涉及溶液相化学，并且能够保留中间体的立体化学。
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