Vints A M, van Saase J L, van Assen G A
Afd. Longziekten, Ziekenhuis Leyenburg, 's-Gravenhage.
Ned Tijdschr Geneeskd. 1990 Mar 31;134(13):657-60.
In the period from August 1981 to April 1987, 169 percutaneous needle biopsies were performed on 149 patients in the Leyenburg Hospital in The Hague, after bronchoscopy had failed to provide a diagnosis. We studied the diagnostic yield and the occurrence of complications. A diagnosis of malignancy was made in 77 out of 98 patients with a final diagnosis of malignancy by other methods than needle biopsy. Sensitivity, specificity and the predictive value of a positive and a negative test were 78%, 100%, 100% and 67% respectively. The risk of complications was 7% (12/169), 5 patients required drainage because of pneumothorax. The low morbidity and the high diagnostic yield make percutaneous needle biopsy a valuable and safe diagnostic procedure.
在1981年8月至1987年4月期间，海牙莱延堡医院对149例患者进行了169次经皮针吸活检，此前支气管镜检查未能做出诊断。我们研究了诊断率和并发症的发生情况。在98例最终通过针吸活检以外的其他方法确诊为恶性肿瘤的患者中，有77例被诊断为恶性肿瘤。阳性和阴性检测的敏感性、特异性及预测值分别为78%、100%、100%和67%。并发症的风险为7%（12/169），5例患者因气胸需要引流。低发病率和高诊断率使经皮针吸活检成为一种有价值且安全的诊断方法。
