Amer E, MacLaughlin E, Rice D, Williams J P, Guy J
Can J Surg. 1981 Sep;24(5):504-6.
Percutaneous aspiration needle biopsy for pulmonary lesions has been practised for many years but has not until recently gained popularity. Further proof of its simplicity, safety and accuracy for both central and peripheral lesions is given in this retrospective study of 181 biopsies performed in a community hospital. The diagnostic yield was higher in neoplastic (87.5%) than in nonneoplastic (68.4%) lesions and higher in malignant (91%) than in benign (58.3%) neoplasms. The larger the lesion the higher was the success rate--95.6% if the lesion was larger than 3 cm. The complication rate was low (14.9%) and there were no deaths. There was no difference in the success rate or the incidence of complications between biopsy done for central or peripheral lesions. The complication rate did not differ between large and small lesions, localized or diffuse. The sample could be used for cell block histologic sectioning, which gave the same diagnostic accuracy as cytologic examination. There were no false-positive cytologic diagnoses. During the procedure the operator (a radiologist in all cases) was able to predict the diagnosis in cases of hamartoma and neurofibroma.
经皮穿刺针吸活检术用于肺部病变已有多年，但直到最近才受到欢迎。在一家社区医院对181例活检进行的这项回顾性研究中，进一步证明了其对中央型和周围型病变的操作简便、安全及准确性。肿瘤性病变（87.5%）的诊断阳性率高于非肿瘤性病变（68.4%），恶性肿瘤（91%）高于良性肿瘤（58.3%）。病变越大，成功率越高——病变大于3 cm时成功率为95.6%。并发症发生率较低（14.9%），且无死亡病例。中央型或周围型病变活检的成功率及并发症发生率无差异。大、小病变，局限性或弥漫性病变的并发症发生率无差异。样本可用于细胞块组织学切片，其诊断准确性与细胞学检查相同。细胞学诊断无假阳性。在操作过程中，操作者（所有病例均为放射科医生）能够在错构瘤和神经纤维瘤病例中预测诊断结果。
