Halberg Franz, Cornélissen Germaine, Singh R B
Halberg Chronobiology Center, University of Minnesota, Minneapolis, MN 55455, USA.
Open Nutraceuticals J. 2011 Jan 1;3:100-111. doi: 10.2174/1876396001003010100.
Evidence on time-dependent effects of drugs and nutrition is succinctly reviewed in order to illustrate and advocate investigations of the timing of nutriceuticals. Emphasis is placed on the merits of coordinated, individually, inferentially, statistically examined sets of N-of-1 studies.
本文简要回顾了关于药物和营养的时间依赖性效应的证据,以阐明并倡导对营养保健品服用时间的研究。重点强调了对N-of-1研究进行协调、单独、推断性、统计学检验的优点。