Singh Sarabjeet, Blevins Mary-Beth, Wakeman Matthew, Bergevin Michael
LifeNet Health, Virginia Beach, VA, USA.
Cell Tissue Bank. 2012 Dec;13(4):565-7. doi: 10.1007/s10561-011-9272-2. Epub 2011 Aug 4.
Tissue recovery personnel often find themselves in a situation in which, upon donor physical assessment, they discover an unusual or suspicious skin or tissue lesion. Because of the concern about the possibility of recovering tissues from a donor who may have an occult malignancy or infection, the Recovery Team may elect not to recover. Otherwise they may continue with the recovery, documenting their concern on the physical assessment form. At the time of evaluation of donor suitability the Medical Director must determine what the lesion is. This is inherently difficult and sometimes has led to the discard of recovered tissues. In order to optimize the gift of donation and avoid unnecessary deferral or discard of tissues we instituted a recovery biopsy procedure several years ago. Between January, 2005 and March, 2010, 561 biopsies were performed. In 552 donors (98.4%) there was no negative effect on medical suitability. Nine donors (1.6%) were found unsuitable based on the biopsy results. The recovery biopsy has allowed Recovery Teams to better manage their time by quickly identifying and biopsying suspicious lesions without trying to make a determination of donor eligibility and possibly ruling ineligible a qualified donor. The recovery biopsy has allowed the Medical Directors to make suitability decisions to accept or reject based on diagnostic certainty.
在对捐赠者进行身体评估时，他们发现了异常或可疑的皮肤或组织病变。由于担心从可能患有隐匿性恶性肿瘤或感染的捐赠者身上回收组织，回收团队可能会选择不进行回收。否则，他们可能会继续进行回收，并在身体评估表上记录他们的担忧。在评估捐赠者的适用性时，医疗主任必须确定病变是什么。这本质上很困难，有时会导致回收的组织被丢弃。为了优化捐赠的善举，避免不必要地推迟或丢弃组织，我们在几年前制定了回收活检程序。在2005年1月至2010年3月期间，共进行了561次活检。在552名捐赠者（98.4%）中，对医疗适用性没有负面影响。根据活检结果，有9名捐赠者（1.6%）被认定不适合。回收活检使回收团队能够通过快速识别并对可疑病变进行活检，更好地管理他们的时间，而不必试图确定捐赠者的资格，也不会将合格的捐赠者判定为不合格。回收活检使医疗主任能够基于诊断的确定性做出接受或拒绝的适用性决定。
