Elleuch E, Hammami B, Smaoui F, Maaloul I, Turki H, Elloumi M, Ben Jemaa M
Service des maladies infectieuses, CHU Hedi-Chaker, Sfax, Tunisie.
Arch Pediatr. 2011 Sep;18(9):966-9. doi: 10.1016/j.arcped.2011.06.003. Epub 2011 Aug 3.
Sweet syndrome is a neutrophilic dermatosis that can lead to various inflammatory and neoplastic pathologies. We report a case of Sweet syndrome revealing acute leukemia at a 13-year-old girl, who had no history of illness. The diagnosis was made in spite of atypical skin lesions and was confirmed by the skin biopsy and the bone marrow examination. In spite of corticosteroid therapy and chemotherapy, the patient died. Sweet syndrome's diagnosis requires an exhaustive etiologic survey. If there is no evidence of underlying disease, patients must be regularly monitored.
Sweet综合征是一种嗜中性皮病,可导致各种炎症性和肿瘤性病变。我们报告一例13岁无病史女孩的Sweet综合征并发急性白血病病例。尽管皮肤病变不典型,但仍作出了诊断,并经皮肤活检和骨髓检查得以证实。尽管进行了皮质类固醇治疗和化疗,患者仍死亡。Sweet综合征的诊断需要进行详尽的病因调查。如果没有潜在疾病的证据,必须对患者进行定期监测。