一种利用坎杜反应堆为核医学集约生产钼-99同位素的策略。
A strategy for intensive production of molybdenum-99 isotopes for nuclear medicine using CANDU reactors.
作者信息
Morreale A C, Novog D R, Luxat J C
机构信息
Department of Engineering Physics, McMaster University, 1280 Main Street, West Hamilton, Ontario, Canada L8S 4L7.
出版信息
Appl Radiat Isot. 2012 Jan;70(1):20-34. doi: 10.1016/j.apradiso.2011.07.007. Epub 2011 Jul 23.
Technetium-99m is an important medical isotope utilized worldwide in nuclear medicine and is produced from the decay of its parent isotope, molybdenum-99. The online fueling capability and compact fuel of the CANDU(®)(1) reactor allows for the potential production of large quantities of (99)Mo. This paper proposes (99)Mo production strategies using modified target fuel bundles loaded into CANDU fuel channels. Using a small group of channels a yield of 89-113% of the weekly world demand for (99)Mo can be obtained.
锝-99m是一种在全球核医学中广泛应用的重要医用同位素，由其母体同位素钼-99衰变产生。坎杜（CANDU）反应堆的在线换料能力和紧凑型燃料使得大量生产钼-99成为可能。本文提出了利用装入坎杜燃料通道的改进型靶燃料束来生产钼-99的策略。通过使用一小部分通道，钼-99的产量可达全球每周需求量的89%-113%。
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