Marsh J W, Blanchardon E, Gregoratto D, Hofmann W, Karcher K, Nosske D, Tomásek L
Health Protection Agency, Radiation Protection Division, Chilton, Didcot, UK.
Radiat Prot Dosimetry. 2012 May;149(4):371-83. doi: 10.1093/rpd/ncr310. Epub 2011 Aug 3.
Epidemiological studies on uranium miners are being carried out to quantify the risk of cancer based on organ dose calculations. Mathematical models have been applied to calculate the annual absorbed doses to regions of the lung, red bone marrow, liver, kidney and stomach for each individual miner arising from exposure to radon gas, radon progeny and long-lived radionuclides (LLR) present in the uranium ore dust and to external gamma radiation. The methodology and dosimetric models used to calculate these organ doses are described and the resulting doses for unit exposure to each source (radon gas, radon progeny and LLR) are presented. The results of dosimetric calculations for a typical German miner are also given. For this miner, the absorbed dose to the central regions of the lung is dominated by the dose arising from exposure to radon progeny, whereas the absorbed dose to the red bone marrow is dominated by the external gamma dose. The uncertainties in the absorbed dose to regions of the lung arising from unit exposure to radon progeny are also discussed. These dose estimates are being used in epidemiological studies of cancer in uranium miners.
正在对铀矿工人进行流行病学研究,以便根据器官剂量计算来量化患癌风险。已应用数学模型来计算每位矿工因接触铀矿粉尘中存在的氡气、氡子体和长寿命放射性核素(LLR)以及外部伽马辐射,每年肺部、红骨髓、肝脏、肾脏和胃部区域所吸收的剂量。描述了用于计算这些器官剂量的方法和剂量测定模型,并给出了单位暴露于每种源(氡气、氡子体和LLR)所产生的剂量。还给出了一名典型德国矿工的剂量测定计算结果。对于这名矿工,肺部中央区域所吸收的剂量主要来自接触氡子体产生的剂量,而红骨髓所吸收的剂量则主要来自外部伽马剂量。还讨论了单位暴露于氡子体导致肺部区域吸收剂量的不确定性。这些剂量估计值正用于铀矿工人癌症的流行病学研究。