Health Protection Agency, Radiation Protection Division, Chilton, Didcot, UK.
Health Phys. 2010 Oct;99(4):511-6. doi: 10.1097/HP.0b013e3181d6bc19.
Epidemiological studies of the occupational exposure of miners and domestic exposures of the public have provided strong and complementary evidence of the risks of lung cancer following inhalation of radon progeny. Recent miner epidemiological studies, which include low levels of exposure, long duration of follow-up, and good quality of individual exposure data, suggest higher risks of lung cancer per unit exposure than assumed previously by the International Commission on Radiological Protection (ICRP). Although risks can be managed by controlling exposures, dose estimates are required for the control of occupational exposures and are also useful for comparing sources of public exposure. Currently, ICRP calculates doses from radon and its progeny using dose conversion factors from exposure (WLM) to dose (mSv) based on miner epidemiological studies, referred to as the epidemiological approach. Revision of these dose conversion factors using risk estimates based on the most recent epidemiological data gives values that are in good agreement with the results of calculations using ICRP biokinetic and dosimetric models, the dosimetric approach. ICRP now proposes to treat radon progeny in the same way as other radionuclides and to publish dose coefficients calculated using models, for use within the ICRP system of protection.
矿工职业暴露和公众家庭暴露的流行病学研究为吸入氡子体后肺癌风险提供了强有力的、互为补充的证据。最近的矿工流行病学研究包括低水平的暴露、长时间的随访和个体暴露数据的高质量,这表明每单位暴露的肺癌风险比国际辐射防护委员会(ICRP)以前假设的更高。虽然可以通过控制暴露来管理风险,但剂量估计对于控制职业暴露是必需的,并且对于比较公众暴露的来源也很有用。目前,ICRP 使用从暴露(WLM)到剂量(mSv)的剂量转换因子来计算氡及其子体的剂量,这些剂量转换因子基于矿工流行病学研究,被称为流行病学方法。使用基于最新流行病学数据的风险估计值来修订这些剂量转换因子,得到的结果与使用 ICRP 生物动力学和剂量学模型进行计算的结果非常吻合,这就是剂量学方法。ICRP 现在提议以与其他放射性核素相同的方式对待氡子体,并公布使用模型计算的剂量系数,供 ICRP 保护系统内使用。