Hansen-Welches Lauren, Slabach Rachel, Landrum Jeffry E, Prahlow Joseph A
From the *Indiana University School of Medicine, Indianapolis, IN; †Department of Anesthesiology, Georgetown University Hospital, Washington, DC; ‡Elkhart County Coroner, Elkhart; §Indiana University School of Medicine-South Bend at the University of Notre Dame; and ∥South Bend Medical Foundation, South Bend, IN.
Am J Forensic Med Pathol. 2011 Sep;32(3):219-22. doi: 10.1097/PAF.0b013e31822a62b7.
The death of an infant younger than 1 year requires a thorough scene investigation and autopsy. Most infant deaths investigated by forensic pathologists can be placed into 2 general categories: sudden infant death syndrome and accidental asphyxial deaths. Despite the fact that most infant deaths occur within these 2 categories, it is important to remember that other entities may be responsible for death. In this report, we present a developmental pulmonary abnormality that was ultimately responsible for the death of an infant. A 6-month-old male infant with a prior history of pneumonia was brought to an emergency department for evaluation of fever. Antibiotics were prescribed, and the child was discharged and sent home with instructions to his mother to follow up with his pediatrician. Later that evening, the infant seemed to be in respiratory distress. His mother again transported him to the emergency department, where, on arrival, he became apneic. Despite vigorous resuscitative efforts, the infant died. Of note at autopsy was the presence of low-set abnormal ears and bilateral inward-turning ankles. Internally, an abnormality of the tracheobronchial tree was evident, with the right upper lobe bronchus arising from the distal trachea, proximal to the carina. In addition, the right upper lobe was discolored and firm. Microscopically, pneumonia was present. The cause of death was pneumonia due to a right tracheal bronchus. Childhood pneumonia is a known cause of childhood hospitalization, morbidity, and mortality. Identifying the causes of recurrent pneumonia, be it structural, metabolic, or syndromic, aids in preventing recurrent infections and reducing the incidence of childhood mortality. A tracheal bronchus, also known as bronchus suis or "pig bronchus," is an anatomic variant of the tracheobronchial tree in which a bronchus arises proximal to the carina, most commonly on the right and predominantly in males. The incidence is around 0.2%. Although the tracheal bronchus is sometimes a clinically silent entity, some patients may exhibit certain signs and symptoms, including hemoptysis, coughing, stridor, wheezing, and pain. The typical consequences of the tracheal bronchus are recurrent pneumonias. The recurrent pneumonia is thought to be due to a stasis of secretions and an abnormal pulmonary clearing mechanism. Treatment for the condition varies, based on symptoms. For asymptomatic patients, conservative management is adequate. For symptomatic patients with persistent atelectasis or right upper lobe consolidation, surgical excision is advised.
1岁以下婴儿死亡需要进行全面的现场调查和尸检。法医病理学家调查的大多数婴儿死亡可分为两大类:婴儿猝死综合征和意外窒息死亡。尽管大多数婴儿死亡属于这两类,但重要的是要记住,其他病因也可能导致死亡。在本报告中,我们介绍了一种最终导致婴儿死亡的发育性肺部异常情况。一名有肺炎病史的6个月大男婴因发热被送往急诊科评估。医生开了抗生素,孩子出院回家,并嘱咐其母亲与儿科医生随访。当晚晚些时候,婴儿似乎出现呼吸窘迫。他的母亲再次将他送往急诊科,到达时他已停止呼吸。尽管进行了积极的复苏努力,婴儿还是死亡了。尸检时值得注意的是,婴儿耳朵位置低且异常,双侧脚踝内翻。在内部,气管支气管树存在异常,右上叶支气管起源于气管远端,靠近隆突。此外,右上叶变色且质地坚硬。显微镜检查显示存在肺炎。死亡原因是右气管支气管导致的肺炎。儿童肺炎是儿童住院、发病和死亡的已知原因。确定复发性肺炎的病因,无论是结构性、代谢性还是综合征性的,都有助于预防反复感染并降低儿童死亡率。气管支气管,也称为副支气管或“猪支气管”,是气管支气管树的一种解剖变异,其中支气管起源于隆突近端,最常见于右侧,且男性居多。发病率约为0.2%。虽然气管支气管有时在临床上无明显症状,但一些患者可能会出现某些体征和症状,包括咯血、咳嗽、喘鸣、喘息和疼痛。气管支气管的典型后果是复发性肺炎。复发性肺炎被认为是由于分泌物淤滞和肺部清除机制异常所致。根据症状不同,该病的治疗方法也有所不同。对于无症状患者,保守治疗就足够了。对于有持续肺不张或右上叶实变的有症状患者,建议手术切除。