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Circulating levels of soluble α-Klotho in patients with chronic kidney disease.

作者信息

Sugiura Hidekazu, Tsuchiya Ken, Nitta Kosaku

机构信息

Department of Medicine, Kidney Center, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan.

出版信息

Clin Exp Nephrol. 2011 Oct;15(5):795-796. doi: 10.1007/s10157-011-0511-4. Epub 2011 Aug 5.

DOI:10.1007/s10157-011-0511-4
PMID:21818545
Abstract
摘要

相似文献

1
Circulating levels of soluble α-Klotho in patients with chronic kidney disease.
Clin Exp Nephrol. 2011 Oct;15(5):795-796. doi: 10.1007/s10157-011-0511-4. Epub 2011 Aug 5.
2
Serum levels of soluble secreted α-Klotho are decreased in the early stages of chronic kidney disease, making it a probable novel biomarker for early diagnosis.血清可溶性分泌型 Klotho 水平在慢性肾脏病早期降低,使其成为早期诊断的一种可能的新型生物标志物。
Clin Exp Nephrol. 2012 Oct;16(5):722-9. doi: 10.1007/s10157-012-0621-7. Epub 2012 Mar 29.
3
Soluble α-klotho and its relation to kidney function and fibroblast growth factor-23.可溶性 α-klotho 及其与肾功能和成纤维细胞生长因子 23 的关系。
J Clin Endocrinol Metab. 2014 May;99(5):E855-61. doi: 10.1210/jc.2013-4171. Epub 2014 Feb 25.
4
Circulating α-klotho levels in CKD and relationship to progression.CKD 患者循环α-klotho 水平及其与进展的关系。
Am J Kidney Dis. 2013 Jun;61(6):899-909. doi: 10.1053/j.ajkd.2013.01.024. Epub 2013 Mar 27.
5
Fibroblast Growth Factor 23 and α-Klotho Protein Are Associated with Adverse Clinical Outcomes in Non-Dialysis CKD Patients.成纤维细胞生长因子 23 和 α-klotho 蛋白与非透析 CKD 患者的不良临床结局相关。
Kidney Blood Press Res. 2020;45(6):900-915. doi: 10.1159/000510351. Epub 2020 Oct 9.
6
No apparent link between serum Klotho and phosphate in human chronic kidney disease.人类慢性肾病中血清α-klotho与磷酸盐之间无明显关联。
Kidney Int. 2016 Jun;89(6):1399-400. doi: 10.1016/j.kint.2015.11.034.
7
Reduction of Oxidative Stress in Chronic Kidney Disease Does Not Increase Circulating α-Klotho Concentrations.慢性肾脏病中氧化应激的降低不会增加循环中α-klotho的浓度。
PLoS One. 2016 Jan 25;11(1):e0144121. doi: 10.1371/journal.pone.0144121. eCollection 2016.
8
[Potential application of fibroblast growth factor 23-klotho axis in chronic kidney disease].成纤维细胞生长因子23-klotho轴在慢性肾脏病中的潜在应用
Nephrol Ther. 2020 Mar;16(2):83-92. doi: 10.1016/j.nephro.2019.05.003. Epub 2019 Dec 13.
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Secreted Klotho and FGF23 in chronic kidney disease Stage 1 to 5: a sequence suggested from a cross-sectional study.慢性肾脏病 1 至 5 期的分泌性 Klotho 和 FGF23:一项横断面研究提示的序列。
Nephrol Dial Transplant. 2013 Feb;28(2):352-9. doi: 10.1093/ndt/gfs460. Epub 2012 Nov 4.
10
Clinical significance of fibroblast growth factor-23 and soluble alpha klotho in different stages of chronic kidney disease.成纤维细胞生长因子-23和可溶性α-klotho在慢性肾脏病不同阶段的临床意义
Saudi J Kidney Dis Transpl. 2019 Jan-Feb;30(1):108-118.

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An evaluation of both serum Klotho/FGF-23 and apelin-13 for detection of diabetic nephropathy.评估血清 Klotho/FGF-23 和 apelin-13 对糖尿病肾病的检测作用。
Hormones (Athens). 2023 Sep;22(3):413-423. doi: 10.1007/s42000-023-00464-4. Epub 2023 Jul 17.
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A Land of Controversy: Fibroblast Growth Factor-23 and Uremic Cardiac Hypertrophy.一片争议之地:成纤维细胞生长因子 23 与尿毒症性心肌肥厚。
J Am Soc Nephrol. 2020 Jul;31(7):1423-1434. doi: 10.1681/ASN.2020010081. Epub 2020 Jun 11.
3
The Prognostic Role of Klotho in Patients with Chronic Kidney Disease: A Systematic Review and Meta-analysis.

本文引用的文献

1
Establishment of sandwich ELISA for soluble alpha-Klotho measurement: Age-dependent change of soluble alpha-Klotho levels in healthy subjects.夹心 ELISA 法的建立用于可溶性 α-Klotho 的检测:健康受试者中可溶性 α-Klotho 水平的年龄相关性变化。
Biochem Biophys Res Commun. 2010 Jul 30;398(3):513-8. doi: 10.1016/j.bbrc.2010.06.110. Epub 2010 Jul 1.
2
Depressed expression of Klotho and FGF receptor 1 in hyperplastic parathyroid glands from uremic patients.尿毒症患者甲状旁腺增生组织中 Klotho 和 FGF 受体 1 的低表达。
Kidney Int. 2010 Feb;77(3):232-8. doi: 10.1038/ki.2009.414. Epub 2009 Nov 4.
3
Amelioration of progressive renal injury by genetic manipulation of Klotho gene.
Klotho 在慢性肾脏病患者中的预后作用:系统评价和荟萃分析。
Dis Markers. 2019 Jun 2;2019:6468729. doi: 10.1155/2019/6468729. eCollection 2019.
4
The role of klotho in chronic kidney disease.Klotho 在慢性肾脏病中的作用。
BMC Nephrol. 2018 Oct 22;19(1):285. doi: 10.1186/s12882-018-1094-z.
5
Correlation between Soluble -Klotho and Renal Function in Patients with Chronic Kidney Disease: A Review and Meta-Analysis.可溶性 Klotho 与慢性肾脏病患者肾功能的相关性:综述与荟萃分析。
Biomed Res Int. 2018 Aug 12;2018:9481475. doi: 10.1155/2018/9481475. eCollection 2018.
6
Soluble klotho may be a marker of phosphate reabsorption.可溶性klotho可能是磷酸盐重吸收的一个标志物。
Clin Kidney J. 2017 Jun;10(3):397-404. doi: 10.1093/ckj/sfw146. Epub 2017 Feb 28.
7
Reduction of calprotectin and phosphate during testosterone therapy in aging men: a randomized controlled trial.老年男性睾酮治疗期间钙卫蛋白和磷酸盐的降低:一项随机对照试验。
J Endocrinol Invest. 2017 May;40(5):529-538. doi: 10.1007/s40618-016-0597-3. Epub 2016 Dec 20.
8
Klotho, the Holy Grail of the kidney: from salt sensitivity to chronic kidney disease.klotho,肾脏的圣杯:从盐敏感性到慢性肾脏病
Int Urol Nephrol. 2016 Oct;48(10):1657-66. doi: 10.1007/s11255-016-1325-9. Epub 2016 May 23.
9
The demonstration of αKlotho deficiency in human chronic kidney disease with a novel synthetic antibody.用新型合成抗体证明人类慢性肾脏病中α-klotho缺乏。
Nephrol Dial Transplant. 2015 Feb;30(2):223-33. doi: 10.1093/ndt/gfu291. Epub 2014 Oct 15.
10
αKlotho and vascular calcification: an evolving paradigm.α-klotho与血管钙化:一个不断演变的范例。
Curr Opin Nephrol Hypertens. 2014 Jul;23(4):331-9. doi: 10.1097/01.mnh.0000447024.97464.a3.
通过对Klotho基因进行基因操作改善进行性肾损伤。
Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2331-6. doi: 10.1073/pnas.0611079104. Epub 2007 Feb 7.
4
Klotho converts canonical FGF receptor into a specific receptor for FGF23.α-klotho将经典成纤维细胞生长因子受体转化为成纤维细胞生长因子23的特异性受体。
Nature. 2006 Dec 7;444(7120):770-4. doi: 10.1038/nature05315. Epub 2006 Oct 29.
5
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.小鼠klotho基因的突变会导致一种类似于衰老的综合征。
Nature. 1997 Nov 6;390(6655):45-51. doi: 10.1038/36285.