Department of Neurological Sciences, Division of Neurosurgery, Center of Excellence for Technological Innovation in Surgery ITC, Federico II University School of Medicine, Naples, Italy.
Neurol Sci. 2011 Dec;32 Suppl 3:S335-9. doi: 10.1007/s10072-011-0709-y.
There is no effective alternative to surgery in the treatment of the symptomatic cases of chiari malformation. Nonetheless, in literature there is no unanimous consensus about what is the surgical "gold standard" and which are the candidates for surgery. No doubt that intracranial hypertension and ventricular dilatation have to be investigated and treated before considering decompression. It is also very important to keep in mind that a surgery does not guarantee a complete recovery from every symptoms. We report our experience about who are the candidates for surgery, which is the most appropriate surgical technique and when is the correct time for surgery along the natural history of the disease.
在治疗有症状的 Chiari 畸形病例中,手术是唯一有效的治疗方法。然而,在文献中,对于什么是手术的“金标准”以及哪些患者适合手术,尚无统一的共识。毫无疑问,在考虑减压之前,必须对颅内压升高和脑室扩张进行调查和治疗。同样重要的是要记住,手术并不能保证每个症状都能完全恢复。我们报告了我们关于哪些患者适合手术、最适合的手术技术以及手术时机的经验,这些都是基于疾病的自然史。