Departamento Toxicología Ambiental, Facultad de Medicina, Universidad Autónoma de San Luis Potosí, Avenida Venustiano Carranza No. 2405, Col Lomas los Filtros, San Luís Potosí 78210, SLP, Mexico.
Arch Environ Contam Toxicol. 2012 Feb;62(2):351-8. doi: 10.1007/s00244-011-9700-0. Epub 2011 Aug 7.
The aim of this study was to assess levels of DDT and DDE in two environmental matrices (soil and dust) and to investigate the blood levels of these insecticides in exposed children living in a north Mexican state (Chihuahua) where DDT was sprayed several years ago during (1) health campaigns for the control of malaria and (2) agricultural activities. DDT and DDE were analyzed by gas chromatography/mass spectrometry. In general, lower levels were found in household outdoor samples. The levels in outdoor samples ranged from 0.001 to 0.788 mg/kg for DDT and from 0.001 to 0.642 mg/kg for DDE. The levels in indoor samples ranged from 0.001 to 15.47 mg/kg for DDT and from 0.001 to 1.063 mg/kg for DDE. Similar results to those found in indoor soil were found in dust, in which the levels ranged from 0.001 to 95.87 mg/kg for DDT and from 0.001 to 0.797 mg/kg for DDE. Moreover, blood levels showed that all of the communities studied had been exposed to DDT and/or DDE, indicating a general past or present exposure to DDT. It is important to note that the quotient DDT/DDE in all matrices was always >1. Whether the people living in our study area are at risk is an issue that deserves further analysis. However, applying precautionary principles, it is important to initiate a risk-reduction program to decrease exposure to DDT and its metabolites in people living in this area.
本研究旨在评估两种环境基质(土壤和灰尘)中的滴滴涕和滴滴伊水平,并调查居住在墨西哥北部恰帕斯州(Chihuahua)的接触儿童的血液中这些杀虫剂的水平。恰帕斯州几年前曾使用滴滴涕(1)用于疟疾控制卫生运动,以及(2)农业活动。滴滴涕和滴滴伊通过气相色谱/质谱法进行分析。一般来说,户外家庭样本中的含量较低。户外样本中滴滴涕的浓度范围为 0.001 至 0.788 毫克/千克,滴滴伊的浓度范围为 0.001 至 0.642 毫克/千克。室内样本中滴滴涕的浓度范围为 0.001 至 15.47 毫克/千克,滴滴伊的浓度范围为 0.001 至 1.063 毫克/千克。室内土壤中发现的结果与灰尘中相似,其中滴滴涕的浓度范围为 0.001 至 95.87 毫克/千克,滴滴伊的浓度范围为 0.001 至 0.797 毫克/千克。此外,血液水平表明所有研究社区都曾接触过滴滴涕和/或滴滴伊,表明过去或现在普遍接触滴滴涕。需要注意的是,所有基质中 DDT/DDT 的比值始终>1。生活在我们研究区域的人是否面临风险是一个值得进一步分析的问题。然而,根据预防原则,有必要启动一个减少风险的计划,以减少生活在该地区的人们接触滴滴涕及其代谢物。