Liu Tai-ping, Fu Yong, Xu Wen-yue
Department of Pathogenic Biology, The Third Military Medeial University, Chongqing 400038, China.
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2011 Feb 28;29(1):64-7.
Cerebral malaria is a severe complication of malaria. Early studies suggest that cerebral malaria is related to cytoadherence of parasitized red blood cells to the microvessel endothelium of brain. However, more and more evidence supported that the cause of cerebral malaria is uncontrolled inflammatory cytokines and infiltration of lymphocytes in brain microvessel. The article summarizes the research progress on immunological mechanism of cerebral malaria.
脑型疟疾是疟疾的一种严重并发症。早期研究表明，脑型疟疾与被寄生红细胞与脑微血管内皮细胞的细胞黏附有关。然而，越来越多的证据支持脑型疟疾的病因是不受控制的炎性细胞因子以及淋巴细胞在脑微血管中的浸润。本文综述了脑型疟疾免疫机制的研究进展。
