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比较阻塞性睡眠呼吸暂停患者舌骨手术中的微创技术。

Comparison of minimally invasive techniques in tongue base surgery in patients with obstructive sleep apnea.

机构信息

Kecioren Training and Research Hospital Department of Otorhinolaryngology, Ankara, Turkey.

出版信息

Otolaryngol Head Neck Surg. 2011 Nov;145(5):858-64. doi: 10.1177/0194599811414793. Epub 2011 Aug 8.

Abstract

OBJECTIVE

To compare the effectiveness and morbidity of 3 microinvasive tongue base surgical procedures combined with uvulopalatopharyngoplasty (UPPP) in supine-dependent obstructive sleep apnea (OSA) patients.

STUDY DESIGN

A prospective, randomized clinical study.

SETTING

A tertiary referral center.

METHODS

Fifty OSA patients were randomly advised to undergo UPPP combined with low-temperature bipolar radiofrequency (group 1), submucosal minimally invasive lingual excision with radiofrequency (SMILE-R; group 2), or submucosal minimally invasive lingual excision with a harmonic scalpel (SMILE-H; group 3). The Epworth Sleepiness Scale, the visual analog scale (VAS) for snoring, the pre- and postoperative 3-month polysomnography (PSG) findings, and the decrease in tongue volume using magnetic resonance imaging (MRI) were compared. The operation times, the postoperative pain VAS score, the analgesic requirement, and the time in commencing a normal diet were compared in the 3 groups.

RESULTS

The decrease in apnea-hypopnea index (AHI) and supine AHI values at the postoperative 3-month time point was significant in group 2 (P < .05). The decrease in tongue volume at the 3-month postoperative time point according to the MRI evaluations was higher in groups 1 and 2 (P < .05). In the subjective comparison of effectiveness, there was no significant difference. The operation time was significantly lower in group 3. In the assessment of postoperative pain, no significant difference was found between the groups.

CONCLUSION

When the PSG findings and MRI were evaluated, UPPP + SMILE-R were found to be more effective. No significant difference was found between the 3 techniques when morbidity and complications were compared.

摘要

目的

比较 3 种微创舌根手术联合悬雍垂腭咽成形术(UPPP)治疗仰卧位相关阻塞性睡眠呼吸暂停(OSA)患者的有效性和发病率。

研究设计

前瞻性、随机临床研究。

设置

三级转诊中心。

方法

50 例 OSA 患者随机接受 UPPP 联合低温双极射频(组 1)、黏膜下微创舌切除联合射频(SMILE-R;组 2)或黏膜下微创舌切除联合超声刀(SMILE-H;组 3)治疗。比较 Epworth 嗜睡量表、打鼾视觉模拟评分(VAS)、术前和术后 3 个月多导睡眠图(PSG)结果以及磁共振成像(MRI)测量的舌体积减少情况。比较 3 组手术时间、术后疼痛 VAS 评分、镇痛需求以及开始正常饮食的时间。

结果

组 2 术后 3 个月时呼吸暂停低通气指数(AHI)和仰卧位 AHI 值的降低有统计学意义(P <.05)。组 1 和组 2 术后 3 个月时 MRI 评估的舌体积减少量较高(P <.05)。在主观疗效比较中,差异无统计学意义。组 3 的手术时间明显较低。在术后疼痛评估中,各组之间无显著差异。

结论

当 PSG 结果和 MRI 评估时,UPPP+SMILE-R 更有效。当比较发病率和并发症时,3 种技术之间无显著差异。

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