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[地塞米松、促肾上腺皮质激素及其联合应用后大鼠肾上腺糖原含量的实验研究(作者译)]

[Experimental investigations of the content of glycogen in the adrenal gland of the rat after application of dexamethasone, ACTH and a combination of both (author's transl)].

作者信息

Ueberberg H, Litz W, Trieb G, Blum H

出版信息

Res Exp Med (Berl). 1979 Feb 6;174(2):177-85. doi: 10.1007/BF01851330.

Abstract

The influence of dexamethasone, ACTH and the combination of both on the glycogen content of the rat adrenal gland was studied. Dexamethasone induces a transient increase of the adrenal glycogen content in a time and dose-dependent manner. The application of ACTH has no effect on the glycogen content. Surprisingly, the increase of the glycogen content induced by dexamethasone is completely blocked by the simultaneous application of ACTH.

摘要

研究了地塞米松、促肾上腺皮质激素(ACTH)以及二者联合应用对大鼠肾上腺糖原含量的影响。地塞米松能以时间和剂量依赖的方式诱导肾上腺糖原含量短暂增加。ACTH的应用对糖原含量无影响。令人惊讶的是,地塞米松诱导的糖原含量增加会被同时应用的ACTH完全阻断。

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