Qi Zhong-Zhi, Tian Rong
Department of Nuclear Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
Sichuan Da Xue Xue Bao Yi Xue Ban. 2011 May;42(3):392-6.
To investigate the impact of patient motion on myocardial perfusion imaging with double-head Single Photon Emission Computed Tomography (SPECT) and assess the effect of motion correction.
Twenty (20) patients were included in the study. Acquisitions were performed for all patients under the situations with or without body motion respectively. Images were reconstructed without or with motion correction software separately. The extent of perfusion defects was assessed by QPS (Quantitative Perfusion SPECT) with a 20 -segment, 5-point scoring system.
The extent of artifacts and perfusion defects was related to the extent (r = 0.58, P < 0.01) and frequency (r = 0.811, P < 0.01) of patient motion. The image quality was improved in 18 of 20 patients (900%) significantly after motion correction (P < 0.05). Only 2.2% (7/318) of segments that were previously considered normal (score = 0 or 1) changed to abnormal (score = 2-4) after motion correction, whereas 35.3% (29/82) of abnormal segments were reclassified as normal after motion correction.
Motion correction is necessary in myocardial perfusion imaging reconstruction if the range of patient motion is out of one pixel or the motion frequency is more than one time. But the correction is not helpful when the extent of body motion exceeds 3 pixel or the motion frequency is over one time.
探讨患者运动对双头单光子发射计算机断层扫描（SPECT）心肌灌注成像的影响，并评估运动校正的效果。
本研究纳入20例患者。分别在患者有或无身体运动的情况下对所有患者进行采集。图像分别在不使用或使用运动校正软件的情况下重建。采用定量灌注SPECT（QPS）的20节段、5分评分系统评估灌注缺损程度。
伪影和灌注缺损程度与患者运动程度（r = 0.58，P < 0.01）和频率（r = 0.811，P < 0.01）相关。20例患者中有18例（90%）在运动校正后图像质量显著改善（P < 0.05）。运动校正后，先前被认为正常（评分 = 0或1）的节段中只有2.2%（7/318）变为异常（评分 = 2 - 4），而异常节段中有35.3%（29/82）在运动校正后重新分类为正常。
如果患者运动范围超出一个像素或运动频率超过一次，在心肌灌注成像重建中进行运动校正是必要的。但当身体运动程度超过3像素或运动频率超过一次时，校正并无帮助。
