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对非洲黑人内分泌病的研究贡献(作者译)

[Contribution to the study of endocrinopathies in black Africans (author's transl)].

作者信息

Sankalé M, Sow A M, Diop B, Bao O, Tounkara-Faye S, Toure Y I, Padonou N, Kaouk M

出版信息

Sem Hop. 1979;55(1-2):14-9.

PMID:218290
Abstract

For a long time endocrine pathology was unrecognized or even denied to exist in Black Africans, but this is not true. It seems to be recognized more frequently since medicalization has increased. This pathology does not present any particularities. Hyperthyroidism appears frequently, at least in urban areas. A series of 87 personal cases has permitted a review of the principal clinical and biological aspects; myasthenia seems to be particularly important; radical treatment is preferred over prolonged medical treatment which is not within the financial possibilities of our patients. There have been 30 observations of cortico-adrenal anomalies of which 7 known personally. It must be noted that the Black living in his traditional rural environment presents a certain degree of physiological hypocorticism with respect to whites and especially Blacks of higher social standing. Pathological hypocorticism is essentially due to tuberculosis; the melanodermia is evident to an alert observer. Metabolic hypercorticism produces the usual manifestations. Only 9 cases of Sheehan syndrome have been reported (5 personal). In the Black African woman, it appears earlier than in Europe often due to premature nuptiulity and the higher incidence of tachyparity. One is surprised that this syndrome is detected so rarely; it is, without a doubt, often well tolerated during a long period of time therefore goes undetected.

摘要

长期以来,内分泌病理学在非洲黑人中未被认识甚至被否认存在,但事实并非如此。自从医疗普及程度提高以来,这种病理学似乎更常被认识到。这种病理学没有任何特殊性。甲状腺功能亢进症很常见,至少在城市地区如此。87例个人病例的系列研究使得对主要临床和生物学方面进行了回顾;重症肌无力似乎尤为重要;根治性治疗优于长期药物治疗,因为长期药物治疗超出了我们患者的经济承受能力。有30例皮质 - 肾上腺异常的观察病例,其中7例是我个人所知。必须指出的是,生活在传统农村环境中的黑人相对于白人和尤其是社会地位较高的黑人表现出一定程度的生理性肾上腺皮质功能减退。病理性肾上腺皮质功能减退主要是由结核病引起的;对于警觉的观察者来说,黑皮症是明显的。代谢性肾上腺皮质功能亢进会产生常见的表现。仅报告了9例席汉综合征病例(5例为个人病例)。在非洲黑人女性中,该综合征比在欧洲出现得更早,这通常是由于早婚和多产的发生率较高。令人惊讶的是,这种综合征很少被发现;毫无疑问,它在很长一段时间内通常耐受性良好,因此未被察觉。

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