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[一例由异环磷酰胺和阿霉素联合控制的巨大网膜源性脂肪肉瘤]

[A case of huge omental-origin liposarcoma controlled by a combination of ifosfamide and adriamycin].

作者信息

Noguchi Tadaaki, Kawamura Muneo, Kawamura Takeshi, Sasaki Kuniaki, Hosono Tomohiro, Sato Rikiya, Murakami Keishiro

机构信息

Dept. of Surgery, Kawamura Hospital.

出版信息

Gan To Kagaku Ryoho. 2011 Aug;38(8):1357-9.

Abstract

A 51-year-old woman came to our hospital after a medical check -up. She suffered from abdominal distension. Abdominal CT revealed the abdominal cavity filled with omental cake. The preoperative diagnosis was unassertive. Laparotomy through midline incision was performed. The bulk of the omental tumor occupied the abdominal cavity, but infiltrated the bowel or abdominal wall less. Fractional resection of the tumor, right hemicolectomy, sigmoidectomy, wedge resection of small intestine and left ovariectomy were performed in parallel. Resected specimens weighed 6. 6 kg in total. The operation was considered palliative because of the peritoneal dissemination. Postoperative intraabdominal administration of cisplatin(50mg) made the ascites disappear. She was discharged 3 weeks after the operation. The final diagnosis was liposarcoma(myxoid type), and 5 courses of adjuvant chemotherapy with adriamycin and ifosfamide were performed. No relapse was found 11 months after the operation, but tumor regrowth occurred in the thoracic and abdominal cavity and the patient died 14 months after the operation.

摘要

一名51岁女性在体检后前来我院就诊。她患有腹胀。腹部CT显示腹腔内充满网膜饼。术前诊断不明确。经中线切口行剖腹手术。大部分网膜肿瘤占据腹腔,但较少浸润肠管或腹壁。并行肿瘤部分切除术、右半结肠切除术、乙状结肠切除术、小肠楔形切除术及左侧卵巢切除术。切除标本总重6.6千克。由于腹膜播散,该手术被认为是姑息性的。术后腹腔内给予顺铂(50毫克)使腹水消失。术后3周出院。最终诊断为脂肪肉瘤(黏液样型),并进行了5个疗程的阿霉素和异环磷酰胺辅助化疗。术后11个月未发现复发,但胸腹腔内肿瘤复发,患者于术后14个月死亡。

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