Section of Pediatric Infectious Diseases, IUNICS, Son Espases University Hospital and University of the Balearic Islands, Palma de Mallorca, The Balearic Islands, Spain.
Pediatr Infect Dis J. 2012 Jan;31(1):97-100. doi: 10.1097/INF.0b013e31822dfbf7.
We present a case of a child with Leishmania infantum cutaneous leishmaniasis unresponsive to 2 courses of intravenous liposomal amphotericin B, a treatment failure that has not been reported in this Leishmania species. The patient responded to topical imiquimod and had no relapse. We review the literature on the treatment failure of liposomal amphotericin B for cutaneous leishmaniasis.
我们报告了 1 例利什曼原虫皮肤利什曼病患儿，该患儿对 2 个疗程的静脉注射两性霉素 B 脂质体无反应，这种利什曼原虫物种的治疗失败尚未有报道。患者对局部咪喹莫特反应良好，且无复发。我们回顾了两性霉素 B 脂质体治疗皮肤利什曼病治疗失败的文献。
