Kawai R, Mori Y, Kawakami K
Department of Radiology, Jikei University School of Medicine.
Rinsho Hoshasen. 1990 Feb;35(2):235-41.
Radionuclide studies for the interstitial lung disease were surveyed in this article. On the ventilation-perfusion study, high V/Q mismatches are seen in advanced stage. A bolus inhalation method of small amount of Kr-81 m gas is useful to detect the impairment of thoraco-pulmonary compliance in the early stage of chronic interstitial pneumonitis (CIP). Ga-67 scintigraphy is indispensable for early detection and assessing the activity of CIP. During the last few years, the assessment of epithelial permeability using Tc-99m-DTPA is performed to evaluate morphological damage of pulmonary parenchyma in interstitial pulmonary diseases. Clinical significance of I-123-IMP scintigraphy was also surveyed.
本文对间质性肺疾病的放射性核素研究进行了综述。在通气-灌注研究中，晚期可见高V/Q不匹配。少量Kr-81m气体的团注吸入法有助于在慢性间质性肺炎（CIP）早期检测胸肺顺应性受损情况。Ga-67闪烁扫描对于CIP的早期检测和评估其活性不可或缺。在过去几年中，使用Tc-99m-DTPA评估上皮通透性以评价间质性肺疾病中肺实质的形态学损伤。还综述了I-123-IMP闪烁扫描的临床意义。
