关于CD4 T细胞如何控制结核分枝杆菌，我们究竟了解多少？ - Suppr

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What do we really know about how CD4 T cells control Mycobacterium tuberculosis?

作者信息

Torrado Egidio, Cooper Andrea M

机构信息

Trudeau Institute, Inc, Saranac Lake, New York, United States of America.

出版信息

PLoS Pathog. 2011 Jul;7(7):e1002196. doi: 10.1371/journal.ppat.1002196. Epub 2011 Jul 28.

DOI:10.1371/journal.ppat.1002196

PMID:21829359

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3145794/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/25b4/3145794/273c6d36312a/ppat.1002196.g001.jpg

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PLoS Pathog. 2011 May;7(5):e1002052. doi: 10.1371/journal.ppat.1002052. Epub 2011 May 19.

Intravital imaging reveals limited antigen presentation and T cell effector function in mycobacterial granulomas.活体成像揭示分枝杆菌肉芽肿中抗原呈递和 T 细胞效应功能有限。

Immunity. 2011 May 27;34(5):807-19. doi: 10.1016/j.immuni.2011.03.022. Epub 2011 May 19.

Role of innate cytokines in mycobacterial infection.固有细胞因子在分枝杆菌感染中的作用。

Mucosal Immunol. 2011 May;4(3):252-60. doi: 10.1038/mi.2011.13. Epub 2011 Mar 23.

A multistage tuberculosis vaccine that confers efficient protection before and after exposure.一种多阶段结核疫苗，可在暴露前后提供高效保护。

Nat Med. 2011 Feb;17(2):189-94. doi: 10.1038/nm.2285. Epub 2011 Jan 23.

Cellular response to mycobacteria: balancing protection and pathology.细胞对分枝杆菌的反应：平衡保护和病理学。

Trends Immunol. 2011 Feb;32(2):66-72. doi: 10.1016/j.it.2010.12.001. Epub 2011 Jan 6.

Pathogen-specific regulatory T cells delay the arrival of effector T cells in the lung during early tuberculosis.病原体特异性调节性 T 细胞在早期肺结核期间延迟效应 T 细胞在肺部的出现。

J Exp Med. 2010 Jul 5;207(7):1409-20. doi: 10.1084/jem.20091885. Epub 2010 Jun 14.

Memory CD4+ T cells induce innate responses independently of pathogen.记忆性 CD4+ T 细胞可独立于病原体诱导先天免疫反应。

Nat Med. 2010 May;16(5):558-64, 1p following 564. doi: 10.1038/nm.2142. Epub 2010 May 2.

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Int Immunol. 2004 Dec;16(12):1691-9. doi: 10.1093/intimm/dxh170. Epub 2004 Oct 11.

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