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结肠镜检查和粪便潜血试验在德国的应用:一项基于大型保险队列的研究结果。

Colonoscopy and fecal occult blood test use in Germany: results from a large insurance-based cohort.

机构信息

Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany.

出版信息

Endoscopy. 2011 Sep;43(9):771-81. doi: 10.1055/s-0030-1256504. Epub 2011 Aug 9.

Abstract

BACKGROUND AND STUDY AIMS

Colonoscopy and guaiac-based fecal occult blood tests (FOBT) are recommended and offered for colorectal cancer (CRC) screening in Germany. We aimed to explore their utilization in a large insurance-based cohort.

PATIENTS AND METHODS

Claims data from between 2000 and 2008 were collected for 170493 individuals who were insured by a large health insurance plan in the federal state of Hesse, Germany. The percentages of individuals who had recently utilized CRC screening-related procedures were calculated. Additionally, multiple test use and identification of CRC screening providers were ascertained.

RESULTS

Following the inception of the current CRC screening program in 2002, colonoscopy utilization rates varied only slightly and FOBT use decreased in individuals aged ≥50 years. At the end of 2008, the age-standardized percentages of individuals who had undergone colonoscopy within ≤10 years were 23% for men and 26% for women. The proportions of individuals who had used FOBT within ≤1 year were 14% for men and 22% for women. Patient education had been utilized by 38% of eligible persons and was increasingly followed by screening colonoscopy. For women, practices that specialized in gynecology were the main providers of FOBT (93%) and patient education (61%).

CONCLUSIONS

This study provides new insights into the inter-related utilization of colonoscopy, FOBT, and patient education in Germany, and may be particularly informative for the design of strategies to increase CRC screening uptake. It indicates that sex differences in CRC screening test use could result to a large extent from general visits to different types of specialist physicians involved in the CRC screening process.

摘要

背景与研究目的

结肠镜检查和基于愈创木脂的粪便潜血试验(FOBT)被推荐并用于德国的结直肠癌(CRC)筛查。我们旨在探索其在大型保险队列中的应用。

患者与方法

收集了 2000 年至 2008 年间在德国黑森州一家大型健康保险公司投保的 170493 名个体的理赔数据。计算了最近使用 CRC 筛查相关程序的个体百分比。此外,还确定了多项检测的使用和 CRC 筛查提供者的识别情况。

结果

在 2002 年当前 CRC 筛查计划启动后,结肠镜检查使用率变化不大,≥50 岁人群的 FOBT 使用减少。2008 年底,≤10 年内接受过结肠镜检查的个体标准化年龄百分比为男性 23%,女性 26%。≤1 年内使用 FOBT 的个体比例为男性 14%,女性 22%。有 38%的合格个体接受了患者教育,并且越来越多地接受了筛查性结肠镜检查。对于女性,妇科专业实践是 FOBT(93%)和患者教育(61%)的主要提供者。

结论

本研究为德国结肠镜检查、FOBT 和患者教育的相互关联使用提供了新的见解,对于制定增加 CRC 筛查参与度的策略可能特别有意义。研究结果表明,CRC 筛查检测使用中的性别差异在很大程度上可能源于涉及 CRC 筛查过程的不同类型专科医生的常规就诊。

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