Punjabi Omar S, Lin Christine F, Chung Hak-Sung, Gill Manjot K
Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Ophthalmic Surg Lasers Imaging. 2011 Aug 11;42 Online:e75-80. doi: 10.3928/15428877-20110804-06.
The authors studied the clinical features, visual field, and spectral-domain optical coherence tomography (SD-OCT) characteristics of peripapillary melanocytoma associated with visual field defects in two eyes of two patients. Both eyes had hyperreflective anterior surface and posterior optical shadowing in the region of peripapillary melanocytoma on SD-OCT imaging. The retinal nerve fiber layer was thin adjacent to these lesions, and this corresponded to the opposite hemifield defect on Humphrey Visual Field testing. Three-dimensional imaging of the melanocytoma revealed an irregular elevation in the peripapillary region. SD-OCT, when used in conjunction with clinical examination and Humphrey Visual Field testing, provided useful information that may assist clinicians in treating patients with peripapillary melanocytoma, particularly when observing them over time.
作者研究了两名患者双眼视乳头周围黑素细胞瘤合并视野缺损的临床特征、视野及频域光学相干断层扫描（SD-OCT）特征。在SD-OCT成像中，双眼视乳头周围黑素细胞瘤区域均有高反射性的前表面和后部光学阴影。与这些病变相邻的视网膜神经纤维层变薄，这与 Humphrey 视野检测中相对的半视野缺损相对应。黑素细胞瘤的三维成像显示视乳头周围区域有不规则隆起。SD-OCT 与临床检查及 Humphrey 视野检测相结合时，可提供有用信息，有助于临床医生治疗视乳头周围黑素细胞瘤患者，尤其是在长期观察这些患者时。
