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15例视盘黑色素细胞瘤的光学相干断层扫描

Optical coherence tomography of optic disk melanocytoma in 15 cases.

作者信息

Shields Carol L, Perez Benjamin, Benavides Raquel, Materin Miguel A, Shields Jerry A

机构信息

Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

出版信息

Retina. 2008 Mar;28(3):441-6. doi: 10.1097/IAE.0b013e31815e9853.

Abstract

OBJECTIVE

To describe the optical coherence tomography (OCT) features of optic disk melanocytoma.

DESIGN AND PARTICIPANTS

Case series including 15 patients.

MAIN OUTCOME MEASURES

OCT characteristics of the tumor.

RESULTS

The mean age of the patients was 42 years. By ophthalmoscopy, the mean basal diameter of the tumor was 2.7 mm, and by ultrasonography, the mean thickness was 1.8 mm. By OCT, the tumor showed a nodular appearance in 14 cases (93%). The tumor displayed a gradual sloping transition from normal retina into the mass, hyperreflectivity at its anterior tumor surface, and dense posterior shadowing with an optically empty appearance in all 15 cases (100%). Thicker tumors displayed thinner anterior hyperreflective borders and denser shadowing. There were no internal qualities of the tumor or disk visible by OCT due to dense shadowing. Other findings of OCT included vitreous seeds in 2 cases (13%) and adjacent retinal edema in 1 case (7%). There were no cases of retinal traction, subretinal fluid, macular edema, or epiretinal membrane in the macula.

CONCLUSIONS

Optic disk melanocytoma shows characteristic features by OCT including a gradual transition from normal retina into nodular tumor, and the mass displays a bright anterior border layer with optically empty internal details.

摘要

目的

描述视盘黑色素细胞瘤的光学相干断层扫描(OCT)特征。

设计与参与者

包含15例患者的病例系列。

主要观察指标

肿瘤的OCT特征。

结果

患者的平均年龄为42岁。通过检眼镜检查,肿瘤的平均基底直径为2.7mm,通过超声检查,平均厚度为1.8mm。通过OCT检查,14例(93%)肿瘤表现为结节状外观。在所有15例(100%)病例中,肿瘤显示从正常视网膜到肿物有逐渐倾斜的过渡,肿瘤前表面呈高反射性,后部有浓密阴影且呈光学空洞样外观。较厚的肿瘤前高反射边界较薄且阴影较浓密。由于浓密阴影,OCT无法显示肿瘤或视盘的内部特征。OCT的其他发现包括2例(13%)有玻璃体播散,1例(7%)有相邻视网膜水肿。黄斑区无视网膜牵拉、视网膜下液、黄斑水肿或视网膜前膜病例。

结论

视盘黑色素细胞瘤在OCT上显示出特征性表现,包括从正常视网膜到结节状肿瘤的逐渐过渡,肿物表现为明亮的前边界层且内部细节呈光学空洞样。

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