Department of Chemistry, The University of Chicago, Illinois 60637, United States.
J Am Chem Soc. 2011 Sep 7;133(35):13880-2. doi: 10.1021/ja206736q. Epub 2011 Aug 16.
An efficient and simple source of nitroso reagents and their oxidation reactions are described. The combination of a Lewis acid and a metal nitrite was applied to the oxidation of silyl enol ethers. Amino acid and peptide derivatives were easily accessed through in situ C-C bond cleavage of fully substituted silyl enol ethers upon oxidation.
描述了一种高效、简单的亚硝基试剂来源及其氧化反应。路易斯酸和金属亚硝酸盐的组合被应用于硅基烯醇醚的氧化。通过氧化完全取代的硅基烯醇醚的原位 C-C 键断裂，很容易获得氨基酸和肽衍生物。
