从毛红椿茎皮中分离得到的两种新柠檬苦素。

Two new limonoids from the stem barks of Chukrasia tabularis var. velutina.

作者信息

Li Yi, Luo Jun, Wang Qiang, Kong Ling-Yi

机构信息

School of Traditional Chinese Medicine, China Pharmaceutical University, Nanjing 210009, China.

出版信息

J Asian Nat Prod Res. 2011 Sep;13(9):781-6. doi: 10.1080/10286020.2011.590799.

DOI:10.1080/10286020.2011.590799

PMID:21830881

Abstract

Two new phragmalin-type limonoid orthoesters, C-15 enolic acyl type and 13/14/18-cyclopropanyl type, named chukvelutilide H (1) and tabularin R (2), together with three known limonoid orthoesters (3-5), were isolated from the stem barks of Chukrasia tabularis var. velutina. The structures of these two new compounds were elucidated on their extensive HR-ESI-MS, 1D, and 2D spectroscopic analysis including HSQC, HMBC, and ROESY experiments.

摘要

从毛红椿（Chukrasia tabularis var. velutina）的茎皮中分离出两种新的苦木素型柠檬苦素原酸酯，即C-15烯醇酰基型和13/14/18-环丙烷基型，分别命名为楝维卢替内酯H（1）和板果苷R（2），以及三种已知的柠檬苦素原酸酯（3-5）。通过广泛的高分辨电喷雾电离质谱（HR-ESI-MS）、一维和二维光谱分析（包括异核单量子相干谱（HSQC）、异核多键相关谱（HMBC）和旋转坐标系核Overhauser效应谱（ROESY）实验）阐明了这两种新化合物的结构。