比较人体测量学指标在预测儿童代谢综合征成分中的作用。

Comparison of anthropometric indices in predicting metabolic syndrome components in children.

机构信息

Department of Cardiology, Marmara University School of Medicine, Istanbul, Turkey.

出版信息

Metab Syndr Relat Disord. 2011 Dec;9(6):453-9. doi: 10.1089/met.2011.0018. Epub 2011 Aug 10.

DOI:10.1089/met.2011.0018

PMID:21830913

Abstract

BACKGROUND

The International Diabetes Federation (IDF) defines metabolic syndrome among children. In addition to the abdominal obesity (waist circumference ≥90 percentile of locally representative sample), the risk criteria for metabolic syndrome includes elevated blood pressure, hypertriglyceridemia, low high-density lipoprotein cholesterol (HDL-C) levels, and elevated fasting glucose. In this study, we compared the association of anthropometric indices with metabolic syndrome risk criteria in 9-year-old children.

METHODS

A cross-sectional study of 9-year-old children (n=1,194) was performed in 2007-2008. Using the international cutoff points and percentiles, we determined subjects with elevated blood pressure, hypertriglyceridemia (≥90 percentile), low HDL-C (≤ 10 percentile), and elevated fasting glucose (≥100 mg/dL). We compared several anthropometric indices [triceps skin-fold thickness (SFT), waist circumference, hip circumference, waist-to-hip ratio, body mass index (BMI) and waist-to-height ratio] and their association with metabolic syndrome risk criteria other than waist circumference among 9-year-old children.

RESULTS

Metabolic syndrome risk criteria were commonly observed among 9-year-old children: 244 students (20.4%) had hypertriglyceridemia and/or low HDL-C, 362 students (30.3%) had elevated blood pressure, and 254 (21.3%) students were overweight or obese. Among covariates of SFT, BMI, waist circumference, waist-to-hip, or waist-to-height ratio categories, the BMI category was the only significant predictor of having two or more metabolic syndrome risk variables [odds ratio (OR)=3.5, 95% confidence interval (CI) 1.69-7.41, P=0.001 for boys and OR=4.7, 95% CI 1.61-13.55, P=0.005 for girls].

CONCLUSIONS

Assessing anthropometric indices is crucial for early detection and prevention of metabolic syndrome among children and adolescents. Age- and sex-specific cutoff points of BMI can be used to screen for the metabolic syndrome and related risk criteria among 9-year-old children.

摘要

背景

国际糖尿病联合会（IDF）定义了儿童代谢综合征。除了腹部肥胖（腰围≥当地代表性样本的第 90 百分位）外，代谢综合征的风险标准还包括血压升高、高三酰甘油血症、低高密度脂蛋白胆固醇（HDL-C）水平和空腹血糖升高。在这项研究中，我们比较了 9 岁儿童的人体测量指数与代谢综合征风险标准的关联。

方法

2007-2008 年对 9 岁儿童进行了横断面研究。使用国际截断值和百分位数，我们确定了血压升高、高三酰甘油血症（≥第 90 百分位）、低 HDL-C（≤第 10 百分位）和空腹血糖升高（≥100mg/dL）的受试者。我们比较了几种人体测量指数[三头肌皮褶厚度（SFT）、腰围、臀围、腰臀比、体重指数（BMI）和腰高比]及其与除腰围以外的 9 岁儿童代谢综合征风险标准的关系。

结果

代谢综合征风险标准在 9 岁儿童中很常见：244 名学生（20.4%）有高三酰甘油血症和/或低 HDL-C，362 名学生（30.3%）有血压升高，254 名学生（21.3%）超重或肥胖。在 SFT、BMI、腰围、腰臀比或腰高比类别的协变量中，BMI 类别是唯一有统计学意义的预测因素，与存在两个或更多代谢综合征风险变量相关[男孩的比值比（OR）=3.5，95%置信区间（CI）1.69-7.41，P=0.001；女孩的 OR=4.7，95%CI 1.61-13.55，P=0.005]。