Department of Botany, Patna University, Patna, India.
Drug Chem Toxicol. 2012 Jan;35(1):32-5. doi: 10.3109/01480545.2011.567273. Epub 2011 Aug 10.
The cytogenetic toxicity of the crude leaf extract of Aloe vera, a medicinal plant, was evaluated in two test systems, onion and Swiss albino mice, using their root tip meristematic and bone marrow cells, respectively. No significant increase in structural abnormalities in chromosomes was observed, but a marked increase in cells with chromosome-number anomalies was found. The extract, however, significantly increased the mitotic index of both cell types.
药用植物库拉索芦荟的粗叶提取物的细胞遗传学毒性，分别在洋葱和瑞士白化病小鼠这两种实验体系中，通过根尖分生组织细胞和骨髓细胞进行了评估。没有观察到染色体结构异常的显著增加，但发现染色体数目异常的细胞明显增多。然而，该提取物显著增加了两种细胞类型的有丝分裂指数。
